Hemophilia Pedigree - Father has hemophilia, mother does not. What is the
outcome for their kids? - Correct answer -His daughters would be carriers.
This is x-link recessive.
Autosomal:
Dominant: - Correct answer -Au
...
Hemophilia Pedigree - Father has hemophilia, mother does not. What is the
outcome for their kids? - Correct answer -His daughters would be carriers.
This is x-link recessive.
Autosomal:
Dominant: - Correct answer -Autosomal: males and females equally affected.
Dominant: non-carrier parents
polymerase chain reaction (PCR) - Correct answer -The process of copying
DNA in the lab. Uses Template DNA, Nucleotides (dNTPS), DNA Polymerase,
and DNA primers.
3 Steps of PCR - Correct answer -1. Denaturation: DNA is heated to 95C to
separate it.
2. Annealing: reaction is cooled to 50C; primers stick to the DNA you want to
copy and add DNA polymerase.
3. Elongation: reaction heated to 70C and DNA polymerase, adding
nucleotides building a new DNA strand.
Base Excision Repair (BER) - Correct answer -How you repair a mutation. BER
is used to repair damage to a base caused by harmful molecules. You remove
the base that is damaged and replace it. *BER removes a single nucleotide*
DNA glycolsylase - sees damaged DNA and removes it.
DNA polymerase-puts the right one back in while DNA ligase seals it.
Mismatch repair (MMR) occurs during: - Correct answer -replication. DNA
polymerase proofreads but sometimes a mismatch pair gets through. MMR
removes a large section of the nucleotides from the new DNA and DNA
polymerase tries again. (Ex: C-T instead of C-A)
Mismatch Repair corrects what kind of DNA damage? - Correct answer -When
a base is mismatched due to errors in replication. Such as G-T instead of G-C.
DNA polymerase comes by and fixes it.
What happens when DNA polymerase binds to DNA to make RNA? - Correct
answer -TRANSCRIPTION! DNA polymerase takes the individual nucleotides
and matches them to the parental sequences to ensure a correct pair. It must
bind with RNA primer to work.
What is needed for DNA replication? - Correct answer -DNA polymerase
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