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ABGC Boards - Final Review Exam.pdf

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The 1/2 life of lithium is about? Answer- 24 hours Fluoxetine is the SSRI with the WD risk? Answer- lowest due to long half life What antipsychotics are good for pts who miss doses of their meds? An ... swerAntipsychotics with long half-lives: 1. Cariprazine(Vrylar): (2-4 days-active metabolites up to 3 weeks) 2. Abilify (3 days) 3. Brexipiprazole (4 days) 4. Pimozide (4-5 days) 5. Pimavanserin (2 days, active metabolites 8 days) Disulfiram's alcohol interactions persist for up to how long after the medication is stopped? Answer- LONG Half life--2-3 days persist up to 2 weeks following stopping What is the only TCA with a long half life? Answer- Protriptyline (Vivactil) Most psychotropics have a medium range 1/2 life of approx? Answer- 24 hours what does "steady state" mean in relation to 1/2 life? Answer- steady state means that you are eliminating the drug at the same overall rate that you are ingesting it Lithium reaches its 'steady state' when? Answer- 5 half lives example: Day 1: Start pt on Lithium 600 mg daily Day 2: (24 hours later) the amount left in his body is 300 mg (day 2 min) because 24 hours has passed--one 1/2 life--therefore the pt has excreted 1/2 of the initial amount. THEN the pt takes his 2nd dose of 600 mg on DAY 2-resulting in a max dose of 900 (300 mg left in body + 600 mg of 2nd dose). DAY 3: starts off with 450 mg (1/2 of the 900 mg in pt's system) and after taking the day 3 600 mg dose, the pt now has a total of 1050 mg. Due to the steady state of Lithium, when do we draw a blood level? Answer- 5 half lives [Show More]

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