Advanced Pathophysiology Midterm 6501 Walden University Exam | graded A+| Updated & Verified | 2024

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A runner has depleted all the oxygen available for muscle energy. Which of the following will facilitate his continued muscle performance? - ✔✔Answer: Anaerobic glycolysis What causes the rapid ... change in the resting membrane potential that initiates an action potential? - ✔✔Answer: Sodium gates open, and sodium rushes into the cell, changing the membrane potential from negative to positive. A 12-year-old male is diagnosed with Klinefelter syndrome. His karyotype would reveal which of the following? - ✔✔Answer: XXY A nurse is reviewing the pedigree chart. When checking for a proband, what is the nurse looking for? - ✔✔Answer: The person who is first diagnosed with a genetic disease An aide asks the nurse why people who have neurofibromatosis will show varying degrees of the disease. Which genetic principle should the nurse explain to the aide? - ✔✔Answer: Expressivity In teaching a patient with cirrhosis, which information should the nurse include regarding cholesterol? - ✔✔Answer: Cholesterol decreases the membrane fluidity of the erythrocyte, which reduces its ability to carry oxygen. When a patient asks what causes cystic fibrosis, how should the nurse respond? Cystic fibrosis is caused by an _____ gene - ✔✔Answer: Autosomal recessiveHow are potassium and sodium transported across plasma membranes? - ✔✔Answer: By adenosine triphosphate enzyme (ATPase) The nurse would be correct in identifying the predominant extracellular cation as: - ✔✔Answer: Sodium The early dilation (swelling) of the cell's endoplasmic reticulum results in: - ✔✔Answer: Reduced protein synthesis What principle should the nurse remember when trying to distinguish aging from diseases? - ✔✔Answer: It is difficult to tell the difference because both processes are believed to result from cell injury. What is the diagnosis of a 13-year-old female who has a karyotype that reveals an absent homologous X chromosome with only a single X chromosome present? Her features include a short stature, widely spaced nipples, reduced carrying angle at the elbow, and sparse body hair. - ✔✔Answer: Turner syndrome A eukaryotic cell is undergoing DNA replication. In which region of the cell would most of the genetic information be contained? - ✔✔Answer: Nucleolus The nurse is teaching staff about the most common cause of Down syndrome. What is the nurse describing? - ✔✔Answer: Maternal nondisjunctionA 50-year-old male was recently diagnosed with Huntington disease. Transmission of this disease is associated with: - ✔✔Answer: Delayed age of onset A patient wants to know the risk factors for Down syndrome. What is the nurse's best response? - ✔✔Answer: Pregnancy in women over age 35 What is the role of cytokines in cell reproduction? - ✔✔Answer: Provide growth factor for tissue growth and development A newborn male is diagnosed with albinism based on skin, eye, and hair appearance. Which finding will support this diagnosis? - ✔✔Answer: Inability to convert tyrosine to DOPA (3,4 dihydroxyphenylalanine) Sodium and water accumulation in an injured cell are a direct result of: - ✔✔Answer: Decreased ATP production A nurse is reading a chart and sees the term oncotic pressure. The nurse recalls that oncotic pressure (colloid osmotic pressure) is determined by: - ✔✔Answer: Plasma proteins The ion transporter that moves Na + and Ca 2+ simultaneously in the same direction is an example of which of the following types of transport? - ✔✔Answer: Symport A 20-year-old pregnant female gives birth to a stillborn child. Autopsy reveals that the fetus has 92 chromosomes. What term may be on the autopsy report to describe this condition? - ✔✔Answer: TetraploidyWhy is potassium able to diffuse easily in and out of cells? - ✔✔Answer: Because the resting plasma membrane is more permeable to potassium Hypothyroidism - ✔✔A disorder caused by a thyroid gland that is slower and less productive than normal, does not produce enough T3 and T4 T3, T4, TSH - ✔✔Diagnosing hypo/hyperthyroidism T3/T4 = thyroid. TSH = Pituitary. T3/T4 abnormality = problem with THYROID. T3/T4 normal + TSH abnormal = Secondary thyroid problem If too much T3/T4, then TSH will be down. Vice Versa. calcium - ✔✔parathyroid glands responsible for regulating ___ levels. metabolism, temperature - ✔✔Thyroid produces hormones T3, T4, and plays big role in __, ___ regulation and growth and development iodine - ✔✔Brain cannot make T3 and T4 without ___ slows - ✔✔hypothyroidism everything ___. stimulates sympathetic nervous system, drowsy, lethargic constipated, food move slows, weight gainbody temp increases Hyperthyroidism - ✔✔excessive activity of the thyroid gland: increased levels of T3, T4 and TSH loss - ✔✔Hyperthyroidism: burning calories at an excessive rate weight ___ stimulates sympathetic nervous system: alert, quick reflexes, increased HR & BP (fight or flight response_ Heat intolerance: increased body temp Active GI: diarrhea anterior pituitary gland - ✔✔the anterior part of the pituitary gland; an endocrine gland whose secretions are controlled by the hypothalamic hormones produces thyroid stimulating hormone (TSH) Cushing's disease - ✔✔(Remember: *UP, UP, UP, DOWN, UP*) HYPERnatremia, HYPERtension, INCREASED blood volume, HYPOkalemia, HYPERglycemiaadrenal cortex - ✔✔outer section of each adrenal gland; secretes cortisol, aldosterone, and sex hormones Aldosterone - ✔✔Hormone that stimulates the kidney to retain sodium ions and water to regulate BP via angiotensin-aldosterone system, retention of sodium and secretes potassium cortisol - ✔✔stress hormone released by the adrenal cortex helps the body deal with stress such as illness or injury increases blood glucose breaks down fats, proteins, carbs electrolyte regulations Negative feedback - ✔✔Hypothalamus releases CRH corticotropin releasing hormone --> pituitary gland releases ATCH adrenocorticotropic hormone --> adrenal cortex to release cortisol increased - ✔✔Cushings disease has ___ secretion of cortisol decreased - ✔✔Addison's disease has __ secretion of cortisol and aldosterone Need to ADD some steroidssyndrome - ✔✔Cushing ___ is when an outside cause results in too much production of cortisol, [Show More]

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