ASCP MLT Study Guide Questions and Answers 100% Correct| Latest Update 2024

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CK Is Associated with Cardiac, Muscles, & Brain Tissue. Elevated CK can be seen in Strokes, Vigorous Exercise, and Muscular Dystrophy - ✔✔Elevated Serum Creatine Kinase Is Associated with What C ... onditions? Incubate at Room Temperature or 4oC to Enhance Weak Expression - ✔✔What Should Be Done if Both Forward and Reverse ABO Results are NEGATIVE? 1.) Waist Line Over: 35 in Women, and 40 in Men 2.) Triglyceride Level over 150 mg/dL 3.) Fasting Blood Glucose over 100 mg/dL 4.) LDL Under: 50 in Women, and 40 in Men 5.) Blood Pressure ≥ 130/85 - ✔✔Parameters to define the presence of metabolic syndrome. Class I: HLA-A, HLA-B, HLA-C Class II: HLA-DR - ✔✔Major Histocompatibility Complex Antigens: Class I & Class II Accumulation of abnormal inorganic acids, associated with diabetic ketoacidosis Excessive loss of bicarbonate, as in severe diarrheaRenal Failure - ✔✔Metabolic Acidosis Caused By: pH: Decreased pCO2: Decreased - ✔✔Metabolic Acidosis Blood Gas Results: Erythroid Value = Sum of all Nucleated RBC Precursors Myeloid Value = Sum of Precursor Neutrophils, Eosinophils, and Basophils *Lymphocytes and Monocytes are NOT counted* Interpreted as overall Bone Marrow Cellularity - ✔✔Myeloid to Erythroid Ratio- (M:E) Ratio: Myoglolbin - ✔✔Earliest Biochemical Marker for Myocardial Infraction Lectin from the seeds of Dolichos Biflorus - ✔✔Anti-A1 Reagent is Made from What? Rickettsia Rickettsii - ✔✔Rocky Mountain Spotted Fever is Transmitted by a Tick Infected with what? Oligopeptide in the blood that cause vasoconstriction of arterioles, increases blood pressure and releases aldosterone. - ✔✔Angiotensin 2Calcium and Phosphate - ✔✔Parathyroid Hormone Regulates what in the Body Non-Pathogenic - ✔✔Barr Bodies are Classified as what? Interferon Gamma - ✔✔Cytokine most important for Increased Macrophage Cell Activity? 28 Days, unless the unit expires sooner. - ✔✔Shelf Life for Irradiated Blood? MCV= 80-100 fL. MCH= 27-31 pg. MCHC= 32-36% - ✔✔Normal Ranges: MCV MCH MCHC MCV= (Hematocrit % / RBC's) x 10 MCH= (Hemoglobin / RBC's) x 10 MCHC= (Hemoglobin / Hematocrit) x 100 - ✔✔Formulas for: MCV MCH MCHCMuscle Mass - ✔✔Creatine Excretion Correlates be with: 37o C for 1 hour - ✔✔If not tested right away Semen should be stored: Light Spin, Followed by a Hard Spin - ✔✔Procedure for preparation of Platelet concentrate from whole-blood: Transferrin Saturation, due to its sensitivity and specificity for iron overload - ✔✔Best way to test for Hereditary Hemochromatosis: Positive QC: Pseudomonas Aeruginosa Negative QC: Escherichia Coli - ✔✔Best Stock Cultures to perform QC testing of oxidase production? Middle Aged Adults - ✔✔What age group is Hereditary Hemochromatosis usually detected? It is caused by the engrafting of immunocompetent T lymphocytes into a severely immunosuppressed recipient. They can be prevented by gamma irradiation of cellular blood components. - ✔✔What is responsible for causing Graft-Versus-Host Reactions? Forward Scatter: Size Side Scatter: Granularity - ✔✔In Flow Cytometry, Forward Scatter and Side Scatter tell us what about the cells?Eosinophils. Crystals have a strong association with parasitic infections or allergic reactions - ✔✔Charcot-Leyden Crystals in stool are breakdown products of what? Used to calculate LDL Cholesterol. LDL = [Total Cholesterol] - [HDL] - [Triglyceride/5] - ✔✔What is the Friedewald Formula, and what does it calculate? Megoblastic Anemia, and Lead Poisoning - ✔✔What Diseases are Cabot Rings associated with? Calcium Ion Selective Electrodes, or ISE's - ✔✔Ionized Calcium is Most Commonly Measured by what Method? Testes and Adrenal Cortex. 1/3 from Testes, 2/3 from Adrenal Cortex in Men 98% from Adrenal Cortex in Women. - ✔✔17-Ketosteroids in Urine, help primarily Asses What Organs? A Clearly Discernible Pattern in the Nucleus of the Interphase Cells. - ✔✔For an ANA Test to be Positive, what MUST be present in Nucleus? Destruction of a neonate's platelets by alloantibodies crossing the placenta from the mother. - ✔✔What Is the Cause of Neonatal Alloimmune Thrombocytopenia?Less than 1% = (200:1) Ratio - ✔✔In a Normal CSF, the Protein Concentration as compared to that in Plasma is Usually Equal to? PMN's are dysfunctional neutrophils that are seen in: Chediak-Higashi Chronic Granulomatous Disease Myeloperoxidase Deficiency - ✔✔What Diseases are Associated with Polymorphonuclear Neutrophils? Amperiometric-Coulometric Titration - ✔✔An Automated Method for Measuring Chloride, Which Generates Silver Ions in the Reaction? Chocolate Blood Agar favors the growth of Fastidious Bacteria. - ✔✔Compared to Blood Agar Media, Chocolate Blood Agar FAVORS the Growth of which Organisms? Peptide Bonds - ✔✔Biuret Reactions, For the Analysis of Serum Proteins are Dependent on the Number of? Chocolate Agar - ✔✔Which Media Contains Both Factor X and V Needed to Grow Haemophilus Influenzae? Carcinoid Tumor - ✔✔A Markedly Elevated 5-Hydroxyindole Acetic Acid (5-HIAA) is Evidence Of?Hb A Hb A2 Hb F - ✔✔Which Hemoglobin's Can Be Decreased in Alpha Thalassemia? Acute Lymphocytic Leukemia - ✔✔Which Leukemia is Most Commonly Diagnosed in Children? CA 15-3 and CA 549 - ✔✔What Tumor Markers are Elevated in More Advanced Stages of Breast Cancer? Bacitracin Susceptibility - ✔✔What Test is Used to Identify Lancefield Group A Streptococcus? Disseminated Intravascular Coagulation (DIC) Thrombotic thrombocytopenic purpura (TTP) Hemolytic-uremic syndrome (HUS) Microthrombi Disposition in Small Vessels (Sheering of RBC as they pass through Fibrin Mesh) - ✔✔What Diseases are Associated with Schistocytes, and How are they Made? 30 mL - ✔✔A 300 µg dose of RhIg can Suppress immunization of How many mL of D+ Blood? Cr51 (Chromium 51) - ✔✔The Radioactive Method Used to Measure Red Cell Survival, Uses what Isotope?Serum Cortisol Overproduction - ✔✔Patients with Cushing's Disease Typically Exhibit What? 7 Days - ✔✔Donor and Recipient Blood Samples Must be Kept for How Long After Transfusion? Yearly - ✔✔How Often Should Fire Drills be Conducted in the Laboratory? T-Lymphocytes - ✔✔Contact Dermatitis is Mediated By? Urine Protein Electrophoresis or Immunoelectrophoresis - ✔✔What Method is Used to Confirm the Presence of Bence-Jones Protein in the Urine? Cryptococcus Neoformans in CSF - ✔✔An India Ink Preparation Is Used on CSF to Identify? Interphase & Metaphase - ✔✔What 2 Stages of Cell Division are Most Important for Reading ANA's? Anti-A, Anti-P1, Anti-Leb, and Anti-M - ✔✔Which Antibodies React Most Strongly at 4 C? 20-40 Inches - ✔✔A Computer Monitor Should be set Approximately How Many Inches Away From Eyes?CC = (Urine Creatine x Urine Flow Rate) / Plasma Creatine - ✔✔Creatine Clearance Formula Hydrostatic Differential in Glomerular Tufts - ✔✔Primary Mechanism Responsible for Glomerular Filtration? Cystine, Leucine, Calcium Oxalate, Sodium Urate, Sulfonamide, Tyrosine, Uric Acid, and Amorphous Urates - ✔✔Crystals Found in Acidic Urine? Proximal Convoluted Tubule - ✔✔Primary Site of Reabsorption of Glomerular Filtrate Hemolytic Disease of the Newborn - ✔✔A Spectrophotometric Scan of Amniotic Fluid is used to help Diagnose What Condition? Splenectomies - ✔✔Pappenheimer Bodies are Usually Seen In Patients Who Have? HIV-1 NAT - ✔✔What Test has Been Recommended by the FDA to Replace the HIV-1 p24 Antigen Test in the Screening of Donated Blood for Infectious Diseases? Neutrophils, Monocytes, and Macrophages - ✔✔Phagocytosis is a Function of Which Cells Type? In the Liver by Hepatocytes - ✔✔Where are Most Acute Phase Proteins Synthesized?Prolonged PT and aPTT, along with Decreased Fibrinogen. Thrombocytopenia and Schistocytes on the PBS are associated with all 3, it's the abnormal coagulation test that distinguishes DIC from the other conditions. - ✔✔What Lab Results Would You Find with DIC, but Not TTP or HUS. LDL (Low Density Lipoproteins) - ✔✔Which Type of Lipoprotein Transports the Majority of Cholesterol to Cells for Steroid Hormone Synthesis or Cell Membrane Incorporation? Minimum Inhibitory Concentration, which is the lowest concentration of antibiotic that inhibits visible vitro growth. - ✔✔MIC is an Acronym for: Protein - ✔✔What Contributes to Specific Gravity, but Not Osmolarity? Relative % of Each Cell Type x Total White Cell Count - ✔✔In Terms of Differential Counts, What Does Absolute Value Describe? Potassium, Sodium, Chloride, Carbon Dioxide (Bicarbonate) - ✔✔An Electrolyte Panel Consists of: Granulocytes - ✔✔Febrile Transfusion Reactions are Caused by Antibodies to What? Lewis - ✔✔What Blood Group Antigen May Show a Cell Typing Change During Pregnancy?Inhibit Cell Wall Synthesis - ✔✔A Patient with Atypical Lymphocytes in Their PBS Should Be Tested For: Pink - ✔✔Host Cells (WBC, and Epithelial Cells) Will Stain What Color on A Gram Stain? Bicarbonate and Chloride - ✔✔What Ions Form an Exchanger to Regulate and Buffer Blood PH? Irradiation of Cellular Products - ✔✔Transfusion Associated Graft Versus Host Disease May Be Prevented By: Perform A DAT on Incompatible Unit - ✔✔What Procedure Should Be Done, If 1 Cross Matched Unit Out OF 5 is Incompatible at the AHG Phase? Butterscotch = Streptococcus Anginosus Grapes = Pseudomonas Aeruginosa Bleach = Eikenella Corrodens Pared Apples = Alcailgenes Faecalis - ✔✔Smell Associated with Bacterial Species Neutrophils, Macrophages/Monocytes, and Lymphocytes - ✔✔What Cells Can Be Found in ALL Types of Body Fluid?Serum Iron is Decreased Transferrin Saturation is Decreased Total Iron Binding Capacity (TIBC) is Increased - ✔✔Classic Signs of Acute Iron Deficiency Anemia? Streptococcus Pneumoniae - ✔✔Most Frequent Cause of Bacterial Meningitis in Older Adults Blood Bank - ✔✔In the US, Which Department is regulated by the FDA? Lupus Erythematosus Rheumatoid Arthritis Systemic Sclerosis - ✔✔Name 3 Diseases Associated with Systemic Autoimmune Rheumatic Diseases (SARD) An Immature Blood-Brain Barrier Elevated Protein in CSF Elevated Bilirubin in the Blood - ✔✔Xanthochromia in A Premature Infant Can Be Caused By: Caffeine-Benzoate - ✔✔Substance Used in Jendrassik-Grof Method to Accelerate the Reaction of Unconjugated Bilirubin with the Diazo Reagent? Glycoproteins - ✔✔Acute Phase Proteins Generally Fall into What Category?Anything Under 15 x 10'6 Spermatozoa/mL - ✔✔What Is Considered a Low Sperm Count? Cholesterol, Lipoprotein, HDL, and Triglycerides - ✔✔Lipid Panel Is Composed of Which Tests? Leptin - ✔✔What Adipocyte Product is an Important Messenger in Metabolism, Signally the Hypothalamus that there are changes in fat stores? 7.2 - ✔✔What Is the Lower Threshold Value for Semen pH from Fertile Men? 1.) Denaturation (Turning Double Stranded DNA into Single Strands) 2.) Annealing/Hybrization (Attachment of Primers to Stand) 3.) Extension (Creating Complementary Strand to Produce New Double Strand DNA) - ✔✔Steps to a PCR Reaction Small Intestines - ✔✔Adult Ascaris Lumbricoides Worms Live Where? Von Willebrand Factor - ✔✔A Defect in What Factor Causes Impaired Platelet Adhesion and Aggregation? 1-6 Degrees Celsius - ✔✔A Refrigerator Used to Store Whole Blood Must Be Able to Maintain A Temp In What Ranges? [Show More]

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