ESSENTIAL CELL BIOLOGY, FOURTH EDITION
CHAPTER 16: CELL SIGNALING
© 2014 GARLAND SCIENCE PUBLISHING
General Principles of Cell Signaling
16-2 For each of the following sentences, fill in the blanks with the best word
...
ESSENTIAL CELL BIOLOGY, FOURTH EDITION
CHAPTER 16: CELL SIGNALING
© 2014 GARLAND SCIENCE PUBLISHING
General Principles of Cell Signaling
16-2 For each of the following sentences, fill in the blanks with the best word or phrase
selected from the list below. Not all words or phrases will be used; each word or phrase
should be used only once.
Cells can signal to each other in various ways. A signal that must be relayed to the entire
body is most efficiently sent by endocrine cells, which produce hormones that are carried
throughout the body through the bloodstream. On the other hand, contact-dependent
methods of cell signaling do not require the release of a secreted molecule and are used
for very localized signaling events. During paracrine signaling, the signal remains in the
neighborhood of the secreting cell and thus acts as a local mediator on nearby cells.
Finally, neuronal signaling involves the conversion of electrical impulses into a chemical
signal. Cells receive signals through a receptor, which can be an integral membrane
protein or can reside inside the cell.
amplification G protein phosphorylation
contact-dependent K+ channel receptor
endocrine neuronal target
epithelial paracrine
16-5 When a signal needs to be sent to most cells throughout a multicellular organism, the
signal most suited for this is a ___________.
(a) neurotransmitter.
(b) hormone.
(c) dissolved gas.
(d) scaffold.
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