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NR 507 Advanced Pathophysiology Midterm Exam Practice Questions with Verified Solutions

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NR 507 Advanced Pathophysiology Midterm Exam Practice Questions with Verified Solutions-Hives (urticaria) are an example of a: - Type 1 hypersensitivity reaction. Anaphylaxis is what type of reaction? - type 1 hyperse ...

NR 507 Advanced Pathophysiology Midterm Exam Practice Questions with Verified Solutions-Hives (urticaria) are an example of a: - Type 1 hypersensitivity reaction. Anaphylaxis is what type of reaction? - type 1 hypersensitivity Which of the following are considered the "first responders" of the innate immune system? - neutrophils Allergic contact dermatitis is an example of what type of hypersensitivity reaction. - type 4 hypersensitivity reaction Type 2 (Cytotoxic) hypersensitivity reactions are mediated by: - IgG or IgM Type 1 hypersensitivity reaction is mediated by - IgE Allergic asthma is an example of - type 1 hypersensitivity reaction type 2 hypersensitivity - tissue specific Primary effector cells of type 2 - macrophages Examples of type 2 reactions - drug allergies, hemolytic anemia, blood transfusion mismatch, allergies against infectious agents Type 2 causes - The cell to be destroyed by the antibody Cell destruction through phagocytosis by macrophages Damage to the cell by neutrophils triggering phagocytosis Natural killer cells to release toxic substances that destroy the target cell Malfunction of the cell without destruction Type 3 hypersensitivity reaction - antigen-antibody response Where does the antibody bind to the antigen in type 3 response? - in blood or body fluids and then circulates to tissue Where does the antibody bind to the antigen in type 1, 2, and 4? - on cell surface Primary effector cell in type 3 - neutrophils example of type 3 reaction - serum sickness type 4 hypersensitivity reaction - cell-mediated response primary mediators of type 4 - lymphocytes and macrophages type 4 mediated by - T lymphocytes and do not use antibodies example of type 4 - localized contact dermatitis (poison ivy) Damage occurs with ABO incompatibility because: - Complement damages RBC membrane causing cell lysis. Which of the following is the underlying pathology for hay fever? - mast cell degranulation The diagnosis for an individual who presents to the office with sudden swollen lips and eyes, shortness of breath and throat tightness after a bee sting is: - anaphylaxis

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