BioChemistry > EXAM > BIOCHEM MIDTERM EXAM 2025/2026 COMPLETE QUESTIONS WITH ANSWERS GUARANTEED PASS | RATED A+ (All)
A 19-year-old male is being evaluated for muscle weakness. Evaluation of a muscle biopsy revealed normal rates of succinate oxidation but very low rates of pyruvate oxidation. Further testing determ... ined normal levels of enzymatic activity in both malate dehydrogenase and pyruvate dehydrogenase. Based on this data, the patient may have a mutation in a gene encoding for which mitochondrial protein? a. Complex I (NADH Q-oxidoreductase) b. Complex II (succinate Q-reductase) c. Complex III (Q-cyt c oxidoreductase) d. Complex IV (Cytochrome c oxidase) e. Complex V (ATP synthase) - Answer>>> a. Complex I (NADH Q-oxidoreductase) A 9-month-old girl is suffering from vomiting, lethargy, and poor feeding behavior. Her mother reports that the symptoms began shortly after the baby was given some cereal and mashed bananas by her grandparents. The baby's symptoms seemed to resolve after breastfeeding was resumed. Which of the following is the most likely diagnosis? a. Deficiency of an enzyme in the metabolism of pentose sugars b. Intolerance of dietary fructose c. Deficiency of an enzyme in the pathway that metabolizes glucose d. Intolerance to dietary galactose - Answer>>> b. Intolerance of dietary fructose Caffeine is a natural inhibitor of phosphodiesterase. If you were to consume a large amount of coffee you would likely see a prolonged response to which of the following stimulants or hormones? a. Insulin b. Glucose c. Cortisol d. Glucagon - Answer>>> d. Glucagon A patient presents to the emergency department with lactic acidosis. A deficiency in thiamine (TPP) is suspected and this will be consistent with a decrease in the activity of which of the following enzymes? a. Aldolase B b. Transketolase c. Glucose 6-phosphate dehydrogenase d. Lactate dehydrogenase e. Pyruvate carboxylase - Answer>>> b. Transketolase [Show More]
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