Advanced Pathophysiology Week 3 Quiz
Question 1
2 / 2 pts
Clinical manifestations of mild to moderate splenomegaly and hepatomegaly, bronze-colored skin, and cardiac dysrhythmias are indicative of which anemia?
...
Advanced Pathophysiology Week 3 Quiz
Question 1
2 / 2 pts
Clinical manifestations of mild to moderate splenomegaly and hepatomegaly, bronze-colored skin, and cardiac dysrhythmias are indicative of which anemia?
Sideroblastic
Aplastic
You Answered
Pernicious
Iron deficiency
Mild to moderate enlargement of the spleen (splenomegaly) and liver (hepatomegaly) occurs. Occasionally, abnormal skin pigmentation (bronze colored) is seen. Heart rhythm disturbances, along with congestive heart failure, are major life-threatening complications related to cardiac iron overload.
Question 2
2 / 2 pts
What is the pathophysiologic process of aplastic anemia?
Autoimmune disease against hematopoiesis by activated immunoglobulins
Inherited genetic disorder with recessive X-linked transmission
Malignancy of the bone marrow in which unregulated proliferation of erythrocytes crowd out other blood cells
Correct!
Autoimmune disease against hematopoiesis by activated cytotoxic T cells
Most cases of AA result from an autoimmune disease directed against hematopoietic stem cells. Cytotoxic T cells (Tc cells) appear to be the main culprits.
Question 3
2 / 2 pts
Pernicious anemia generally requires continued therapy lasting
6 to 8 weeks.
Correct!
the rest of one’s life.
until the iron level is normal.
8 to 12 months.
PA cannot be cured, so maintenance therapy is lifelong.
Question 4
2 / 2 pts
Symptoms of polycythemia vera are mainly the result of
destruction of erythrocytes.
Correct!
increased blood viscosity.
neurologic involvement.
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