Pharmacology > EXAM > NUR 2060 (PHARMACOLOGY) INTRO LECT EXAM 1 2025/2026 COMPLETE QUESTIONS WITH CORRECT ANSWERS GUARANTE (All)
Why is it not appropriate to drink grapefruit juice while taking some types of medications? - Answer>>> Interferes with enzymes that break drugs down which increases concentration (statins, CA channe... l blockers) What is bioavailability? - Answer>>> the portion or percentage of an administered dose of a drug that is absorbed, enters circulation, and able to cause an effect Federal Pure Food and Drug Act (1906) - Answer>>> -Very weak Act (no safety/effectiveness req) -Free of adulterants -Required labeling of contents How many half-lives does it take to reach a plateau/steady-state in the blood stream? - Answer>>> 4 half-lives Steady State or Plateau (pharmacokinetics concept) - Answer>>> rate of administration = rate of excretion (also- what concept is this apart of?) Loading Dose (pharmacokinetics concept) - Answer>>> large initial dose followed by a smaller maintenance dose to reach therapeutic effect more rapidly (also- what concept is this apart of?) FDA Food, Drug Cosmetic Act (1938) - Answer>>> -First Act for safety -Animal testing req Harris-Kefauver Ammend. (1962) - Answer>>> -Additional Safety & Effectiveness -must be proven effective & appropriate for use [Show More]
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