1. Which pharmacokinetic process mainly shapes the first part of a plasma concentration-time curve for a given drug?
a) Excretion
b) Distribution
c) Absorption
d) Metabolism
2. Which statement best describes the
...
1. Which pharmacokinetic process mainly shapes the first part of a plasma concentration-time curve for a given drug?
a) Excretion
b) Distribution
c) Absorption
d) Metabolism
2. Which statement best describes the properties of a typical "drug receptor?”
a) It is a bottle used to store pills
b) It is a cell protein with which a drug can interact (i.e. bind to)
c) It is a cell protein to which a drug binds to induce a physiological change
d) It is a gene sequence in the nuclear DNA with which a drug interacts
3. How does the Hippocratic corpus describe verdigris, an ingredient in some of its medical recipes?
a) flowers of sulphur
b) flowers of copper
c) flowers of nitre
d) flowers of Zeus
4. Typical signs of brain damage (neurotoxicity) accompanying heavy exposure to alcohol before birth include which of the following?
a) Lowered IQ scores
b) Behavioural problems
c) Poor socialisation skills
d) All of the above
5. At the level of its effects on GABA receptors in the brain, the effects of ethanol resemble those of which pair of substances?
a) Cocaine and benzodiazepines
b) Anaesthetics and antidepressants
c) Cannabis and benzodiazepines
d) Benzodiazepines and anaesthetics
6. Which of these medical traditions is thought to have pioneered the use of mercury-based medicines?
a) Mesopotamian medicine
b) Greek medicine
c) Islamic medicine
d) Ayurvedic medicine
7. The drug Antabuse causes drinkers to experience more overt hangover symptoms because it inhibits which enzyme?
a) Alcohol dehydrogenase
b) Cytochrome P450
c) Carbonic anhydrase
d) Aldehyde dehydrogenase
8. Jaundice - the yellow coloration of the skin in sufferers of alcoholic hepatitis - is due to subcutaneous accumulation of which of the following metabolites?
a) Bilirubin
b) Ammonia
c) Creatinine
d) Acetaldehyde
9. Which of the following correctly describes the actions of adrenaline and metoprolol at their target receptor?
a) Adrenaline acts as an agonist, metoprolol acts as an antagonist
b) Adrenaline acts as an agonist, metoprolol acts as an agonist
c) Adrenaline acts as an antagonist, metoprolol acts as an agonist
d) Adrenaline acts as an antagonist, metoprolol acts as an antagonist
10. Which of the following is NOT a component of the scientific method of inquiry?
a) Test a theory by additional experiments
b) Develop an idea
c) Use a theory that is not supported by evidence
d) Test the idea by an experiment
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