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MN 553 Final Exam Study Guide

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Final Exam Study Guide Disease states in which beta blockers are utilized  Heart failure  Left ventricular dysfunction  Post acute MI  Essential tremor  Migraine prophylaxis  ... Hyperthyroidism  Hypertension  Angina  Glaucoma Peptic ulcer disease, H. Pylori treatment  Triple therapy of PPI, clarithromycin, and amoxicillin  Sometime flagyl  Doxycycline  Levofloxacin  tetracycline Drug distribution with aging patients  Total body fat increases  SubQ Fat decreases  Decrease in lean muscle mass by 20%  Decrease in total body water by 10-15%  Little subcutaneous fat reduces absorption of transdermal drugs  Lipophilic drugs- increased volume of distribution, accumulation in fat tissue, prolonged duration but decreased immediate effect  Hydrophilic drugs- decreased VD, magnified effects, increased bioavailability with IM drugs  Increased potential for drug toxicity  Increased blood-brain barrier permeability leaves them more susceptible to drugs in the CNS Recommendations for heart failure, class specific  Stage A- high risk for heart failure but without structural heart disease or symptoms o Treat HTN o Smoking cessation o Treat lipid disorders o Encourage regular exercise o Discourage alcohol and drug use o ACE inhibition or ARB  Stage B- structural heart disease but without symptoms of heart failure o All measures under A o ACE inhibitor [Show More]

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