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Rush University - NSG 533 Module 10 Shock Sepsis MODS Objectives Study Guide. Latest 2021

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Rush University - NSG 533 Module 10 Shock Sepsis MODS Objectives Study Guide. Latest 2021.Define the terms infection, bacteremia, systemic inflammatory response syndrome (SIRS), sepsis, septic shock,... and multiple organ dysfunction syndrome (MODS) o Infection: invasion of normally sterile tissue/organism with some infectious organism(s) o Bacteremia: presence of viable infectious bacteria in the blood o Systemic Inflammatory Response Syndrome (SIRS): non specific systemic inflammation; may or may not be infectious o Shock: cellular/tissue hypoxia due to either decreased 02 deliver, increased 02 consumptions and/or inadequate 02 utilization  What is shock? The inability of the body to maintain adequate cell & tissue perfusion  Shock results in the inability to maintain VS, oxygenation, glucose delivery/use, removal waste product o Sepsis: Life threatening organ dysfunction caused by dysregulated host response to an overwhelming infection o Septic Shock: subset of sepsis with circulatory and cellular/metabolic dysfunction requiring intervention and associated with higher risk of mortality than sepsis alone o Multi Organ Dysfunction Syndrome (MODS): progressive organ dysfunction, normal homeostasis cannot be maintained without intervention(s)  Compare and contrast etiology, risk factors and pathophysiology of cardiogenic, hypovolemic, anaphylactic, neurogenic, and septic shock states o All shock states have this in common:  Inadequate tissue perfusion  impaired cellular metabolism  Decreased oxygenation – decreased delivery and/or increased demand  Decreased delivery of nutrients – decreased delivery and/or increased demand  Decreased removal of cellular waste products o Cardiogenic Shock  Cardiogenic shock results from the inability of the heart to pump adequate blood to tissues and end organs from any cause, most common being the short-term consequences of an acute MI or a severe episode of myocardial ischemia  Cardiogenic shock is defined as persistent hypotension and tissue hypoperfusion caused by cardiac dysfunction in the presence of adequate intravascular volume and left ventricular filling pressure  Pathologic conditions that reduce contractility, cause pump failure, impair diastolic filling, or cause obstruction can lead to cardiogenic shock:  Decreased contractility/pump failure: o Acute MI, cardiomyopathy, sepsis, myocarditis, pericarditis, aneurysm, dysrhythmias, contusion, metabolic abnormalities, papillary muscle rupture  Impaired diastolic filling: o Related to dysthymias  Obstruction: o Attributable to pulmonary embolism, cardiac tamponade, valvular disorders, tumors, and wall rupture/defect [Show More]

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