1. The major impact of the physiological changes that occur with aging is:
A. Reduced physiological reserve
B. Reduced homeostatic mechanisms
C. Impaired immunological response
D. All of the above
____ 2. The strong
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1. The major impact of the physiological changes that occur with aging is:
A. Reduced physiological reserve
B. Reduced homeostatic mechanisms
C. Impaired immunological response
D. All of the above
____ 2. The strongest evidence regarding normal physiological aging is available through:
A. Randomized controlled clinical trials
B. Cross-sectional studies
C. Longitudinal studies
D. Case control studies
____ 3. All of the following statements are true about laboratory values in older adults except:
A. Reference ranges are preferable
B. Abnormal findings are often due to physiological aging
C. Normal ranges may not be applicable for older adults
D. Reference values are not necessarily acceptable values
____ 4. Biochemical individuality is best described as:
A. Each individual’s variation is often much greater than that of a larger group
B. The unique biochemical profile of a selected population
C. The truly “normal” individual—falling within average range
D. Each individual’s variation is often much smaller than that of a larger group
____ 5. Polypharmacy is best described as taking:
A. More than nine medications per day
B. More than five medications per day
C. Even a single medication if there is not a clear indication for its use
D. When a drug is given to treat the side effect of another drug
____ 6. Pharmacokinetic changes with aging is reflective of:
A. What the drug does to the body
B. What the body does to the drug
C. The effect at the site of action and the time and intensity of the drug
D. The side effects commonly associated with the drug
____ 7. All the following statements are false about drug absorption except:
A. Antacids increase the bioavailability of digitalis
B. Gastric acidity decreases with age
C. Anticholinergics increase colonic motility
D. Underlying chronic disease has little impact on drug absorption
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