Topic: Week 3: Discussion- Current Event
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Week 3: Di
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Topic: Week 3: Discussion- Current Event
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This is a graded discussion: 100 points possible due Mar 18
Week 3: Discussion- Current Event
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This week we will explore current events related to epidemiology. You will present a scientific article to
the class. Please focus on interpreting the research question, methodology, results, and conclusions
from a sample of peer-reviewed scientific literature. Please be sure the article is related to
epidemiology, summarizing its contents for the class, and providing a succinct written summary.
Current events must have been published within the last six months. Written summaries should
include:
State the objectives of the study
Summarize the study design and findings
Provide a reference of the article
Provide your opinion on how the "average" reader will respond to the article. Will the article
influence decision making or thinking? Does the article leave out any important information?
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(https:// Tina Grinsteiner
(hps://chamberlain.instructure.com/courses/24843/users/22975
Mar 11, 2018
Dr. Weaver and Classmates,
The current event article I choice related to epidemiology is "Epidemiology Data on the
Effectiveness of Influenza Vaccine--Another Piece of the Puzzle.
https://academic.oup.com/jid/advance-article/doi/10.1093/infdis/jix635/4816917
This study was based on the effectiveness of the vaccine for influenza and defined vaccine
effectiveness as the reduction in the risk of an outcome associated with the vaccination. The study
was based on the effectiveness of the inactivated influenza vaccine against medically attended
respiratory complications which were associated with the H1N1 over the course of five years from
5/9/2018 Topic: Week 3: Discussion- Current Event
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seven US centers using an observational study based on the test-negative results. The findings
resulting from the study showed that the vaccine effectiveness between 2010 to 2014 and 2015 to
2016 were 69%, 56% and 47% respectively. However with the 2015 to 2016, the study analyzed
the observed reduction on vaccine effectiveness by also using the difference age categories which
found that the estimated vaccine effectiveness was 22% for those born between 1958 and 1979
(Cheng & Subbarao, 2018). It was believed that influenza strains that were encountered early in
life had a long-lasting effect on the immune response as well as vaccinations. However, the study
showed that 60% of the serological responses to the inactivated influenza vaccines are actually
due to the boost of pre-existing antibodies instead of the new vaccine antibodies and the degree of
protection will continue to vary from season to season and may be lower in certain population
groups and that current vaccines are at the most moderately effective against influenza and need
improvement (Cheng & Subbarao, 2018).
Unfortunately, the data presented would be difficult for the average individual to understand and
comprehend, leaving them to focus only on the conclusion of the study leading the average
individual to believe that the influenza vaccine is ineffective in protecting them against the virus
and would opt not to receive the vaccine without understanding the risks and complications
associated with the influenza virus that they are placing themselves in and those around.
Unfortunately, as we have seen over the course of the last couple of years, less and less
individuals are receiving the influenza vaccine due to the decrease in the vaccines effectiveness
which have lead to an increase in hospitalization and even death related to complications
associated with the influenza virus, specifically H1N1 and sub-types of the viruses. What the
average individual fails to recognize or understand, is the influenza viruses gradually evolve from
year to year making it more difficult to produce an effective influenza vaccine.
Tina
Cheng, A., & Subbarao, K. (2018). Epidemiological data on the effectiveness of influenza vaccineAnother piece of the puzzle. The Journal of Infectious Diseases, jix635.
https://doi.org/10.1093/infdis/jix635
(http Holly Mullen
(hps://chamberlain.instructure.com/courses/24843/users/4682
Mar 13, 2018
Tina,
Thank you for your post. I also examined an article regarding the influenza vaccine in this
week’s TD! This seems like an interesting research study. It is damaging that this virus has so
many sub-types that can change and replicate differently every year.
5/9/2018 Topic: Week 3: Discussion- Current Event
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Annually, influenza causes 250,000 – 500,000 deaths. Further, 5- 10% of adults and 20- 30%
of children will become symptomatic from this illness. This is 3 to 5 million individuals every
year (Puig-Barberà et al., 2016)!
The World Health Organization has increased influenza surveillance since the 2009 pandemic
influenza season. It is vital to understand the epidemiological and virological data related to
illness such as influenza (Puig-Barberà et al., 2016).
The study of epidemiology is essential when determining what causes diseases, examining
risk factors, and investigating how disease is transmitted. Finding causal factors for disease
and eliminating exposure can reduce morbidity and mortality. Likewise, prevention programs,
vaccines, and treatments regimes can prevent transmission of illness. It is vital in evidencebased healthcare to examine how illness, such as influenza, can affect healthcare delivery
systems, communities, and the history of disease prognosis (Gordis, 2014).
Thank you for your post!
Holly Mullen
References
Gordis, L. (2014). Epidemiology (5th ed.). Philadelphia, PA: Elsevier Saunders.
Puig-Barberà, J., Burtseva, E., Hongjie, Y., Cowling, B. J., Badur, S., Kyncl, J., Sominina, &
GIHSN. (2016). Influenza epidemiology and influenza vaccine effectiveness during the 2014-
2015 season: annual report from the Global Influenza Hospital Surveillance Network. BMC
Public Health, 16(1), 1-21. doi:10.1186/s12889-016-3378-1
(http Amy Weaver (Instructor)
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Mar 13, 2018
Reply (1 like)
Holly, thanks for your additional feedback. So many deaths are caused each year by
the flu, yet people often don't seem to give it enough respect to get themselves and
their children vaccinated.
(http Amy Weaver (Instructor)
Mar 13, 2018
Reply (1 like)
Tina, thanks for this great information on the influenza vaccine and disease. I have found it
interesting that some seasons the vaccine is much more effective than it is in others. I
know many people who don't get a flu vaccine due to this high unpredictability of it's
effectiveness. Even in years of lower effectiveness, some protection is certainly better than
none. Wouldn't you agree?
(http Holly Mullen
(hps://chamberlain.instructure.com/courses/24843/users/46
Mar 14, 2018
Dr. Weaver,
Thank you for your feedback. I agree some protection is definitely better than none!
In the United States the CDC recommends annual seasonal influenza vaccination for all
individuals greater than 6 months of age. Recognizing the need for ongoing treatment and
prevention, the CDC estimates the effectiveness of the influenza vaccination in intervals.
Despite unpredictability associated to type of virus, the influenza vaccine remains
recommended by the Centers of Disease Control to prevent infections related to current
circulating virus. Vaccination continues to prevent thousands of hospitalizations and death
(Flannery et al., 2018).
The CDC has collected data from nearly 5,000 children and adults with medically
attended, laboratory confirmed influenza infection in the United States from November 2,
5/9/2018 Topic: Week 3: Discussion- Current Event
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2017- February 3, 2018. Data was collected from five study sites with outpatient medical
facilities. The predominate virus during this season is influenza A(H3N2). It is estimated
that the influenza vaccine effectiveness this year is 36% (Flannery et al., 2018).
The CDC recommends vaccination to reduce complications and risk of illness related to
the flu. It is important to note that other types of influenza virus are still circulating. While
the CDC will continue to monitor the effectiveness of vaccination, providers must
recognize treatment with antiviral medications as an adjunct to vaccination is of utmost
importance (Flannery et al, 2018)!
Thank you,
Holly Mullen
References
Flannery, Chung, Belongia, McLean, Gaglani, Murthy, Zimmerman, Nowalk, M. Jackson,
L. Jackson, Monto, Martin, Foust, Sessions, Berman, Barnes, Spencer, & Fry. (2018).
Interim Estimates of 2017-18 Seasonal Influenza Vaccine Effectiveness - United States,
February 2018. MMWR: Morbidity & Mortality Weekly Report, 67(6), 180-185.
doi:10.15585/mmwr.mm6706a2
(http Allyson Hiers
(hps://chamberlain.instructure.com/courses/24843/users
Mar 16, 2018
Holly,
“Influenza virus can be transmitted from persons infected with influenza virus, even
those with subclinical infections to individuals who are at higher risk of complications
from influenza such as immune-compromised and elder patients. Healthcare facilities
are perfect places for th
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