Recent 2022 Modules from Georgette.
Questions with accurate answers. Rated
A+
What factors decrease renal clearance? - Ans-Kidney Disease
NSAIDs
Hydrochlorothiazide
ACE Inhibitors ("Prils")
What psychotropic is ma
...
Recent 2022 Modules from Georgette.
Questions with accurate answers. Rated
A+
What factors decrease renal clearance? - Ans-Kidney Disease
NSAIDs
Hydrochlorothiazide
ACE Inhibitors ("Prils")
What psychotropic is mainly excreted in the kidneys? - Ans-Lithium
Gabapentin
What makes adults more sensitive to psychotropics? - Ans-Decreased intracellular water
Decreased protein binding (drugs dont have protein to bind to, free floats in blood stream)
Low muscle mass
Increased body fat
Where is Norepinephrine produced? - Ans-Locus Ceruleus
Medullary Reticular Formation
What is serotonin also known as? and where is it produced? - Ans-Also known as indole
Raphe Nuclei of the brainstem
where is dopamine produced? - Ans-Substantia Nigra
Ventral Tegmental Area
Nucleus Accumbens
Where is Acetylcholine synthesized? - Ans-Nucleus Basalis or Basal Nucleus of Meynert
Which receptors do benzodiazepines bind to? - Ans-GABA receptors to potentiate
calming/anxiolytic effects
Autism Spectrum Disorder - Ans-persistent deficits in social communication and social
interaction across multiple contexts:
Lacks Social reciprocity
Nonverbal communication
Unable to efficiently develop, maintain and understand relationships
Restricted repetitive behavior
Stereotyped or repetitive movements
Insistence on samenessClock Drawing Test - Ans-The client is asked to reproduce the face of a clock set to a specific
time. This test may detect difficulties with visuospatial skills, visual perception, selective
attention, memory, abstract thinking, and executive functioning.
Fastest screening tool for possible dementia
Takes 2 mins
Dopamine Pathway responsible for positive symptoms of schizophrenia - Ans-Mesolimbic
pathway - excess dopamine
Dopamine pathway responsible for negative symptoms of schizophrenia - Ans-Mesocortical
pathway - decreased dopamine
How do FGAs differ from SGAs as far as mechanism of action? - Ans-FGAs deplete dopamine
levels in both mesolimbic and mesocortical pathways which helps in reducing positive symptoms
but may worsen negative symptoms.
SGAs decrease excess dopamine in mesolimbic pathways reducing positive symptoms, while
increasing dopamine in mesocortical pathway improving negative symptoms
SGAs also have 5HT2A antagonism properties
Blockage of dopamine in this pathway increases Acetylcholine which causes EPS - AnsNigostriatal pathway
*acetylcholine has inverse relationship with dopamine
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