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BIOD210 Module 6 Exam Genetics/ Questions & Answers

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True or False: A chromosomal ablation is an alteration to the chromosome that results in a change to the total number of chromosomes, deletions or additions to the chromosome, or even complete rearrangement of chromos ...

True or False: A chromosomal ablation is an alteration to the chromosome that results in a change to the total number of chromosomes, deletions or additions to the chromosome, or even complete rearrangement of chromosomal segments. True Corrrreecctt!! False Question 2 2 / 2 pts True or False: Sex chromosomes can occur in pairs but also exist alone with no phenotypic consequence. True Corrrreecctt!! False Question 3 2 / 2 pts True or False: Trisomy and monosomy in autosomal chromosomes are generally not tolerated in animals or plants. True Corrrreecctt!! False Question 4 4 / 4 pts Your Answer: What is the only trisomy disorder in which individuals routinely live longer than one year? The incidence of this disorder seems to increase with an increased age in which parent? down syndrome the mother Down syndrome (trisomy 21) is trisomy disorder in which individuals routinely live longer than one year, the incidence of which seems to increase with maternal age. Question 5 2 / 2 pts True or False: Individuals that are afflicted with Down syndrome typically exhibit only a subset of the stereotypical characteristics of the disorder. Corrrreecctt!! True False Question 6 2 / 2 pts The DSCR region thought to be typically responsible for the Down syndrome phenotype is located on chromosome _____. 20 Corrrreecctt!! 21 3 8 Question 7 6 / 6 pts Your Answer: Why do researchers think that individuals with Down syndrome are protected from cancers that cause solid tumors? because of a gene called DSCR1 that encodes for protein that blocks vascular epithelial growth factor. the tumors cant grow when this function is blocked The DSCR region that is responsible for the phenotype of Down syndrome holds a gene called DSCR1, which encodes for a protein that blocks VEGF (vascular epithelial growth factor). VEGF stimulates the growth of blood vessels, which is extremely important for the vasculature of tumor cells. By blocking VEGF, tumor cells cannot develop the vasculature necessary for the support of tumor growth.

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