ANCC Review Questions (PMHNP IQ)
Already Passed
What direct-acting dopamine receptor agonist is recommended to be used in the treatments of
neuroleptic malignant syndrome (NMS) fo help lower the dopamine blockade? ✔✔B
...
ANCC Review Questions (PMHNP IQ)
Already Passed
What direct-acting dopamine receptor agonist is recommended to be used in the treatments of
neuroleptic malignant syndrome (NMS) fo help lower the dopamine blockade? ✔✔Bromocriptine
(Parlodel) is the recommended direct acting dopamine receptor agonist to help decrease the
dopamine blockade. Danrolene (Dantrium) is a muscle relaxant. Benzotropine (Cogentin) and
Trihexyphenidyl (Artane) are anticholinergic medications used for extrapyramidal side effects
(EPS).
Mr. Smith is a 56 year old white male who has been successfully treated on Selegiline for over 4
years. Mr. Smith is going in for elective surgical procedure. Which medication is strictly
contraindicated with Selegiline? ✔✔Meperidine is strictly prohibited when a patient is treated on
a monoamine oxidase inhibitor (MAOI) due to the risk of hypertensive crisis and death.
A WBC of 4,000 in a patient taking Clozapine would prompt the PMHNP to take which of the
following actions? ✔✔Institute twice-weekly complete blood count with differentials and monitor
closely.
The recommended cut-points for discontinuation of clozapine are WBC of 2,000 to 3,000 or
granulocytes of 1,000 to 1,500 for agranulocytosis and severely compromised immune system. At
a WBC of 4,000, the recommendation is to closely monitor CBC with differential twice a week
while patient may continue clozapine in the absence of any other signs or symptoms.
A patient with a diagnosis of schizophrenia has a history of suicidal ideation and suicide attempts.
The PMHNP should consider which antipsychotic medication that is the only antipsychotic to
reduce the risk of suicide in schizophrenia? ✔✔Clozaril (clozapine) is the only known
antipsychotic medication that had been shown to reduce the risk of suicide in patients diagnosed
with schizophrenia.
A patient being treated for major depressive disorder and on sertraline (Zoloft), 150 mg po daily
for the past 16 years, presents to the psychiatric mental health practitioner for an outpatient followup visit. During the visit she states that she has not been feeling well, reporting the flu. She also
states she has not taken her medication in the last five days. Which of the following symptoms
would she be describing if you suspect selective serotonin reputable inhibitors (SSRIs)
discontinuation syndrome? ✔✔A) Agitation; nausea, dysphoria, and disequilibrium
The patient has SSRI discontinuation syndrome and would be presenting with flu-like symptoms.
If the patient had serotonin syndrome, she would present with symptoms of autonomic instability.
Which of the following statements reflect the current understanding of dopamine (DA) pathways
and clinical symptoms in schizophrenia? ✔✔A) Negative symptoms are related to DA deficit in
the cerebral cortex; positive symptoms are related to DA excess in the nucleus accumbens and
mesolimbic system.
Negative symptoms & cognitive impairment are thought to be related to hypoactivity of the
mesocortical dopiminergic tract, which by its association with the prefrontal cortex and neocortex
contributes to motivation, planning, sequencing of behaviors in time, attention, and social
behavior. Positive symptoms (hallucination and delusions) are thought to be caused by dopamine
hyperactivity in the mesolimbic tract, which regulates emotion. This hyperactivity could result in
overactive modulation of nueurotransmission from the nucleus accumbens.
Norepinephrine is a neurotransmitter that is implicated in alertness and anxiety. What area of the
brain has a large majority of norepinephrine neurons? ✔✔Locus coeruleus
There are two areas in the brain that produce norepinephrine neurons, one is the locus coeruleus
and the other is the medullary reticular formation.
Which cytochrome (CYP) enzyme is implicated as a tobacco inducer when an individual is treated
on clozapine? ✔✔A) 1A2
When an individual is treated on clozapine and decreases tobacco use, the clozapine level with
increase, as tobacco is an inducer to the clozapine, and the patient no longer needs the higher dose
of clozapine.
When working with an avoidant patient with a history of trauma, what type of communication
techniques are helpful? ✔✔Techniques to increase arousal
Activation is needed to allow memories stored in the amygdala to be processed.
The PMHNP knows that the ego is a part of the personality and is the logical/rational mind
including defense mechanisms. What might t
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