Besides hyposecretion and hypersecretion, endocrine system dysfunction can result
from:
a.
abnormal receptor activity.
b.
abnormal hormone levels.
c.
increased synthesis of second messengers.
d.
extracellular e
...
Besides hyposecretion and hypersecretion, endocrine system dysfunction can result
from:
a.
abnormal receptor activity.
b.
abnormal hormone levels.
c.
increased synthesis of second messengers.
d.
extracellular electrolyte alterations. - ANSWER--ANS: A
Dysfunction may result from abnormal cell receptor function or from altered intracellular
response to the hormone-receptor complex. Abnormal hormone levels can occur but
are not the cause of endocrine dysfunction. Intracellular storage of second-messenger
hormones would not lead to dysfunction; receptor function does. Extracellular electrolyte
alterations may result from dysfunction, but they are not a cause.
REF: p. 460
What is the most common cause of elevated levels of antidiuretic hormone (ADH)
secretion?
a.
Autoimmune disease
b.
Cancer
c.
Pregnancy
d.
Heart failure - ANSWER--ANS: B
The most common cause of elevated levels of ADH is cancer, not autoimmune
disorders, pregnancy, or heart failure.
REF: p. 461
A 54-year-old patient with pulmonary tuberculosis is evaluated for syndrome of
inappropriate ADH secretion (SIADH). Which electrolyte imbalance would be expected
in this patient?
a.
Hyponatremia
b.
Hyperkalemia
c.
Hypernatremia
d.
Hypokalemia - ANSWER--ANS: A
Hyponatremia occurs due to increased water reabsorption by kidneys. Hyperkalemia
does not occur due to increased water reabsorption. Sodium levels are lowered with
hyponatremia; they are not elevated. Hypokalemia does not occur; SIADH is a problem
of sodium.
A 44-year-old patient with pulmonary tuberculosis is evaluated for SIADH. Which
assessment finding would support this diagnosis?
a.
Peripheral edema
b.
Tachycardia
c.
Low blood pressure
d.
Concentrated urine - ANSWER--ANS: D
Clinical manifestations of SIADH include urine that is inappropriately concentrated with
respect to serum osmolarity. Symptomology of SIADH does not include peripheral
edema, tachycardia, or low blood pressure.
[Show More]
