BioChemistry > QUESTIONS & ANSWERS > BioChem C785 - WGU - Module 2 - all questions and Answers with Verified Solutions (All)

BioChem C785 - WGU - Module 2 - all questions and Answers with Verified Solutions

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BioChem C785 - WGU - Module 2 - all questions and Answers with Verified Solutions A dehydration reaction builds a polypeptide, where as a hydrolysis reaction breaks a polypeptide Correct Answer- True A misfolded protein can: Correct Answer- 1. can protein aggregation 2. lose normal function 3. can be degraded by the cell 4. can be the result of denaturation A substrate binds to an enzyme at a specific site is referred to as Correct Answer- an active site After learning about Alzheimer's disease and one of the drugs used in its treatment, what other drug design strategies could you use to offer treatment for AD? Correct Answer- 1. Drugs that break up the amyloid plaques 2. Drugs that block the production of amyloid beta peptide 3. drugs that inhibits the aggregation of protein structures Aggregation of the proteins is the main reason behind many neurodegenerative diseases. What mutations will likely cause a neurodegenerative disease? Correct Answer- Replacing a polar amino acid with a non polar amino acid Alkaline phosphatase is produced by bone and liver in the human body. The amount of alkaline phosphatase in blood can help identify if a patient potentially has certain types of bone and/or liver-related disease, including Paget disease, hepatitis, and certain types of cancer. The optimal pH range for alkaline phosphatase activity is a pH of 8.0 to 10.0. What happens to the activity of the alkaline phosphatase at a pH of 2? Correct Answer- Significantly decreasesAlzheimer's disease is caused by aggregation of the Amyloid beta peptide and tangle formation by the tau protein. What kinds of amino acids are likely to drive the formation of these protein aggregates? Correct Answer- hydrophobic An enzyme increases the rate of a chemical reaction by: Correct Answer- decreasing the activation energy Chymotrypsin is a digestive enzyme that has optimal activity at a pH of 7.8 and a temperature of 37 degrees C Correct Answer- 1. At a temperature of 20 degrees C, chymotrypsin will demonstrate increased activity compared to a reaction at 37 degrees C 2. At a pH of 9.5, chymotrypsin will have increased activity compared to a chymotrypsin at a pH of 7.2 3. At a temperature of 90 degrees C, chymotrypsin activity will decrease slightly Compared to a patient that is not on a statin medication, In a patient taking a statin medication the concentration of cholesterol would decrease, the concentration of HMG-CoA would increase, and the concentration of Acetoacetyle CoA would stay the same Correct Answer- True

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