ATI Pharmacology Review with Complete Solutions-Good One!!

ATI Pharmacology Review with Complete Solutions-Good One!! Cephalosporin ✔✔-broad spectrum -ceph/cefs -Similar to PCN/ don't give if PCN allergy -can cause bleeding w/ other bleeding meds monitor bleeding time (tons ...

ATI Pharmacology Review with Complete Solutions-Good One!! Cephalosporin ✔✔-broad spectrum -ceph/cefs -Similar to PCN/ don't give if PCN allergy -can cause bleeding w/ other bleeding meds monitor bleeding time (tonsil story) - Disulfiram reaction (puke & puke & puke) just like Flagyl, the protozoal drug - Store in fridge & take with food ALL antibiotics have these side effects ✔✔- allergy, hypersensitivity - suprainfection - organ (kidney & ear) toxicity - lowers OC effectiveness Vancomyocin ✔✔- serious infections like MRSA - colitis by c-diff - ototoxicity: get hearing test, tell dr. if hearing getting worse -given over 60 minutes Tetracyclines ✔✔- Sumycin, Doxycycline (Vibramycin) - broad, rocky mtn fever, lyme disease, acne, GI infections by H. Pylori - bad GI discomfort - Don't give to kids ≤8; teeth permanently yellow - Bad photosensitivity- wear sunscreen! - Can't take with milk, iron, or antacids - Take on empty stomach with a full glass of water When is Arythromycin given? What class of drugs is it? worse adverse effect? ✔✔When pt allergic to PCN and needs abx. Bacteriostatic inhibitor bad GI issues Aminoglycosides ✔✔ototoxicity, Renal toxicity, Can't take with PCN at all! - gentamicin, neomycin, streptomycin TMP-SMZ ✔✔-Contains Sulfa - use for UTI - Blood problems; get CBC baseline -photosensitivity wear sunscreen and glasses! - empty stomach with a full glass of water Isoniazid (INH) ✔✔-antiTB - take daily for 6-12 months and most likely with other meds too -worked if 3 neg. sputum cultures, no temp. - Liver toxicity (hepato) check liver fxn - Don't take with alcohol (liver fxn remember?) - Take on empty stomach Antiviral: Acyclovir, Ganciclovir ✔✔Teratogenic preg. X; put on rubber gloves if topical! remember my purple glove experience -thrombocytopenia, lowers WBC What class of drugs if Flagyl? What is the weird effect it has? ✔✔protozoal. works on C. diff & H. Pylori PUD. Antibuse effect if taken with alcohol Amphotericin B ✔✔anti-fungal. HIGHLY TOXIC - infusin rxns (fever and chills) - nephrotoxicity - hypokalemia - hepatoxicity - gynecomasita - C/I with aminoglycosides (just like PCN) -azole ✔✔Fungal ______ causes malignant hyperthermia. Use ____ to stop it ✔✔succinylcholine, Dantrium/Dantrolene. Morphine adverse effects ✔✔-Constipation -Resp depression -urinary retention -Sedation - Orthostatic HOTN - Cough suppression Morphine drug-drug interactions (think of what morphine does to the body) ✔✔- MAOIs -anticholinergics -CNS depressants -hypotensive drugs -opiod antagonists (narcan) - antihistamines Morphine patient education re how to take ✔✔Take with food for N/V, lie still will help Opiod withdrawl (stop abruptly is taking ≥6weeks). Is it life-threatening? Will it subside? ✔✔sweating, restless, agitated, dilated pupils, tremors, tachycardia, increased BP, N/V, cramps, muscle spasms with kicking movements. NO, subside in 7-10 days. Migraine medicine & can you take them right after each other? ✔✔vasoconstriction, ergot's and triptans. NO, space out ergot and triptan by at least 24 hours. What pain meds reduces fever? ✔✔ibuprofen, tylenol What pain med reduces platelet aggregation? ✔✔NSAIDS (aspirin), reduce thrombus but will bleed easier, too What pain med reduces fever but has NO anti-inflammatory effect and NO platelet effect? ✔✔tylenol What can give child Reye's syndrome if they have viral illness? ✔✔Aspirin NSAIDS education w/ how to take med. NSAIDS= ✔✔with food, milk, or full glass of water to reduce gastric discomfort. Ibuprofen, Celebrex, Naproxen, Aspirin acetaminophen max dose/day? ✔✔4 grams When to withhold morphine/opiates ✔✔RR <12/min & notify Dr Triptans & pregnancy ✔✔Triptan= Teratogenic. Pregnancy X Rheumatoid Arthritis Drugs name potent toxi