Pharmacology EDAPT - Glucocorticoid
(prednisone)
prednisone is the most commonly prescribed oral glucocorticoid - ✔✔oral
prednisone is a(n) intermediate acting systemic - ✔✔intermediate
Unlike other glucocorticoids,
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Pharmacology EDAPT - Glucocorticoid
(prednisone)
prednisone is the most commonly prescribed oral glucocorticoid - ✔✔oral
prednisone is a(n) intermediate acting systemic - ✔✔intermediate
Unlike other glucocorticoids, prednisone has minimal impacts on . - ✔✔fluid-electrolyte balance
Like the other intermediate-acting glucocorticoids, the half-life of prednisone is __________
giving it a longer duration of action than short-acting corticosteroids. - ✔✔18-36 hours
Which terms describe prednisone? Select all that apply. - ✔✔Systemic
Synthetic
Intermediate-acting
prednisone is a ____ corticosteroid
prednisolone is the _____ form of prednisone converted by the liver - ✔✔solid
liquid
Why should prednisone be used cautiously with immunocompromised individuals? -
✔✔prednisone is an immunosuppressant
Why is it important to taper the daily dosage of prednisone with long-term use? Select all that
apply. - ✔✔HPA axis time
adrenal suppression
Which statements are true regarding long-term use of prednisone (corticosteroids)? Select all that
apply. - ✔✔After as little as 1 week of use, abrupt discontinuation of prednisone can result in
adrenal suppression.
The presence of corticosteroid drugs over a long period of time causes the body's own
(endogenous) corticosteroid production to stop.
Which of the following patients is the MOST at risk for developing adrenal suppression and
subsequent hypoadrenal crisis if this dose is stopped abruptly? - ✔✔A patient taking prednisone
50 mg/day for the last 3 months
Which statement is true regarding the indications of prednisone use? - ✔✔Prednisone, unlike
other corticosteroids, has only minimal mineralocorticoid effects (in addition to glucocorticoid
effects) and therefore it is used in conjunction with a mineralocorticoid to treat chronic
respiratory illnesses such as asthma
Which of the following are glucocorticoid brand names for prednisone? - ✔✔prednisolone,
triamcinolone, methylprednisolone, and hydrocortisone
Choose the correct word(s) to complete these sentences regarding prednisone. - ✔✔prednisone is
a SYNTHETIC corticosteroid
prednisone is a GLUCOCORTICCOID
prednisone is only administered SYSTEMICALLY
prednisone is only administered ORALLY
prednisone is a(n) INTERMEDIATE ACTING
How does prednisone differ from the other three intermediate-acting glucocorticoids? - ✔✔Has
minimal impact on fluid-electrolyte balance
Prednisone, as with all corticosteroids, is classified as a pregnancy category C drug. What does
this mean? - ✔✔it can be secreted in breast milk and should be used cautiously with
breastfeeding.
Considering the action of glucocorticoids, choose the types of medications that should be used
cautiously with prednisone and match them to the associated reason for this caution. -
✔✔Anticoagulation: bloodthinners
Prednisone...: immunosuppressants
Increase the half life: oral contraceptives
Reduction in hypoglycemic effects: antihypertensives
Additive GI effects: NSAIDS
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