Pharmacology EDAPT - Salicylates
(aspirin)
Salicylates (aspirin) are used as which of the following? Select all that apply. - ✔✔anti
inflammatory
antipyretic
analgesic
ASPIRIN is commonly used to prevent myocardial
...
Pharmacology EDAPT - Salicylates
(aspirin)
Salicylates (aspirin) are used as which of the following? Select all that apply. - ✔✔anti
inflammatory
antipyretic
analgesic
ASPIRIN is commonly used to prevent myocardial infarctions and transient ischemic attacks. -
✔✔
To which class of medications do salicylates belong? - ✔✔Nonsteroidal antiinflamatory
(NSAIDs)
Aspirin is commonly used to prevent which of the following conditions? Select all that apply. -
✔✔MI
TIA
Aspirin is a(n) IRREVERSIBLE inhibitor of COX-1 receptors within the platelets themselves.
It causes a(n) REDUCTION in the formation of thromboxane A2 a substance that normally
PROMOTES platelet aggregation - ✔✔
Routes of administration for salicylates (aspirin) include which of the following? Select all that
apply. - ✔✔rectal, oral
Which of the following is a contraindication for use of aspirin? - ✔✔Bleeding disorders
Reyes syndrome is an ACUTE and and potentially life-threatening condition that can cause
progressive and possibly permanent NEUROLOGIC damage - ✔✔
A patient is admitted with salicylate toxicity. Upon assessment, which manifestation is
associated with salicylate toxicity? - ✔✔hyperglycemia
Which of the following is a contraindication for aspirin due to the risk of Reye's syndrome? -
✔✔8 year old with influenza
Which of the following are adverse effects of salicylates (aspirin)? Select all that apply. - ✔✔GI
bleeding
Tinnitus
Please complete the chart with the onset, peak and duration for Aspirin via PO route: -
✔✔Onset: 5-30minutes
Peak: 1-3 hours
Duration: 3-6 hours
Aspirin is absorbed from the upper SMALL INTESTINE
It is distributed quickly and DOES
Aspirin is metabolized by the LIVER and excreted by the KIDNEY - ✔✔
Which of the following are actions of salicylates (aspirin)? Select all that apply. - ✔✔Irreversible
inhibitor of COX-1 receptors within platelets
Reduces of thromboxane A2 formation
Inhibits prostaglandin production
Please complete the chart with the correct half-life for low-dose and high-dose aspirin: - ✔✔Low
dose: 2-3 hours
High dose: 15-30 hours
When administering aspirin for myocardial infarction (MI), which of the following are true?
Select all that apply. - ✔✔Aspirin is shown to reduce cardiac death following MI
Administer aspirin at the first sign of MI
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