1. Pharmaceutic Phase:
2. A tablet (capsule), taken PO, goes through 3 phases. What are the 3 phases?
3. True/False:
When a drug is administered SubQ, IM, or IV, there is a pharmaceutic phase.
4. Disintegration
...
1. Pharmaceutic Phase:
2. A tablet (capsule), taken PO, goes through 3 phases. What are the 3 phases?
3. True/False:
When a drug is administered SubQ, IM, or IV, there is a pharmaceutic phase.
4. Disintegration:
5. Dissolution:
6. True/False:
Drugs in liquid form are more rapidly available for GI absorption than are solids.
7. Pharmacokinetic Phase:
8. What are the 4 processes of Pharmacokinetics?
9. Absorption:
10. 3 types of Absorption:
11. The GI membrane is composed of ___________ & ___________________, so that drugs which are lipid soluble pass rapidly through the GI membrane.
12. True/False:
Water-soluble drugs do not need a carrier to pass through the membrane.
13. Large particles pass through the cell membrane if they are ___________________________.
14. Drugs that are lipid soluble and nonionized are absorbed _____________ than water-soluble and ionized drugs.
15. What can affect drug absorption?
16. True/False:
Drugs given IM are absorbed faster in muscles that have more blood vessels than in those that have fewer blood vessels.
17. First-Pass Effect:
18. Bioavailability:
19. When does Bioavailability occur?
20. The % of bioavailability for the oral route is always _________ 100%, but for the IV route it is always ___________.
21. What factors alter bioavailability?
22. Distribution:
23. Drug distribution is influenced by what?
24. VD
25. True/False:
Drugs with a smaller volume of drug distribution have a longer half-life and stay in the body longer
26. Protein binding:
27. Free drugs:
28. Patients with liver or kidney disease, or malnourished, have low albumin. What does this mean?
29. How do nurses prevent drug toxicity from happening to a patient?
30. True/False:
Most older adults are more likely to have hypoalbuminemia.
31. What is the Blood-Brain Barrier?
32. Drugs that are not bound to proteins and are not lipid soluble are not able to cross the BBB, which makes it difficult to ________________ the drug.
33. Metabolism:
34. What is the primary site of metabolism?
35. A large % of drugs are lipid soluble, thus the liver metabolizes the lipid-soluble drug substances to a __________________________________ for renal excretion.
36. True/False:
Liver disease such as cirrhosis and hepatitis do not alter drug metabolism.
37. When drug metabolism rate is ______________, excess drug accumulation can occur and lead to toxicity.
38. ______________________ of a drug is the time it takes for one half of the drug concentration to be eliminated.
39. A short t 1/2 is considered to be ______________________, and a long t 1/2 is _______________________.
40. The main route of drug elimination is through the _________________.
41. Creatinine Clearance:
42. _____________ is the study of the way drugs affect the body
43. True/False:
Drug response can cause a primary or secondary physiological effect or both.
44. What is the difference between primary and secondary physiologic effects?
45. Does Response:
46. Onset of Action:
47. Peak Action:
48. Duration of Action:
49. What is the Time-Response Curve?
50. Minimum Efficacy Concentration (MEC):
51. Minimum Toxic Concentration (MTC):
52. __________________ is a drug that produces a drug response.
53. _______________________ are drugs that block a response.
54. Nonspecific drugs:
55. Nonselective drugs:
56. 4 categories of drug action include:
57. Therapeutic Index:
58. Peak Drug Level:
59. Trough Drug Level:
60. Loading Dose:
61. Side Effects:
62. Adverse Reactions:
63. Two types of antibiotics are?
64. Bacteriostatic Drugs:
65. Bactericidal:
66. What are the ways Antibacterial affect the body?
67. Superinfection:
68. Narrow spectrum:
69. Broad spectrum:
70. Signs/Symptoms of Viruses:
71. Non-classified antivirals only attack ____________________.
72. What are the side effects of Nonclassified antivirals?
73. what do Neuraminidase Inhibitors attack?
74. Side Effects of Neuraminidase Inhibitors:
75. True/False:
Bacteria is more resistant to the 1st generation vs the 4th generation.
76. Contraindications of Penicillin (Amoxicillin & Dicloxacillin)
77. Interactions of Penicillin (Amoxicillin & Dicloxacillin):
78. Side Effects of Penicillin (Amoxicillin & Dicloxacillin):
79. Adverse Reactions of Penicillin (Amoxicillin & Dicloxacillin):
80. MOA of Penicillin (Amoxicillin & Dicloxacillin):
81. Uses of Penicillin (Amoxicillin & Dicloxacillin):
82. Contraindications of Cephalosporins (Ceftriaxone):
83. Interactions of Cephalosporins (Ceftriaxone):
84. Side Effects of Cephalosporins (Ceftriaxone):
85. Adverse Reactions Cephalosporins (Ceftriaxone):
86. MOA of Cephalosporins (Ceftriaxone):
87. Uses of Cephalosporins (Ceftriaxone):
88. Contraindications of Macrolides (Azithromycin):
89. Interactions of Macrolides (Azithromycin):
90. Side Effects of Macrolides (Azithromycin):
91. Adverse Reactions of Macrolides (Azithromycin):
92. MOA of Macrolides (Azithromycin):
93. Uses of Macrolides (Azithromycin):
94. Side Effects of Lincosamides:
95. MOA of Lincosamides:
96. Side Effects of Vancomycin:
97. MOA of Vancomycin:
98. Uses of Vancomycin:
99. MOA of Ketolides:
100. Uses of Ketolides:
101. Side Effects of Ketolides:
102. Contraindications of Tetracyclines (Doxycycline):
103. Interactions of Tetracyclines (Doxycycline):
104. Uses of Tetracyclines (Doxycycline):
105. Side Effects of Tetracyclines (Doxycycline):
106. MOA of Tetracyclines (Doxycycline):
107. Adverse Reactions of Tetracyclines (Doxycycline):
108. Contraindications of Aminoglycosides (Gentamicin Sulfate):
109. Interactions of Aminoglycosides (Gentamicin Sulfate):
110. Uses of Aminoglycosides (Gentamicin Sulfate):
111. MOA of Aminoglycosides (Gentamicin Sulfate):
112. Side Effects of Aminoglycosides (Gentamicin Sulfate):
113. Adverse Reactions of Aminoglycosides (Gentamicin Sulfate):
114. Contraindications of Fluoroquinolones (Levofloxacin):
115. Interactions of Fluoroquinolones (Levofloxacin):
116. Side Effects of Fluoroquinolones (Levofloxacin):
117. Uses of Fluoroquinolones (Levofloxacin):
118. MOA of Fluoroquinolones (Levofloxacin):
119. Adverse Reaction of Fluoroquinolones (Levofloxacin):
120. Contraindications of Sulfonamides (Trimethoprim - Sulfamethoxazole):
121. Interactions of Sulfonamides (Trimethoprim - Sulfamethoxazole):
122. Uses of Sulfonamides (Trimethoprim - Sulfamethoxazole):
123. Side Effects of Sulfonamides (Trimethoprim - Sulfamethoxazole):
124. MOA of Sulfonamides (Trimethoprim - Sulfamethoxazole):
125. Adverse Reactions of Sulfonamides (Trimethoprim - Sulfamethoxazole):
126. Contraindications of Purine Nucleosides (Acyclovir Sodium):
127. Interactions of Purine Nucleosides (Acyclovir Sodium):
128. Uses of Purine Nucleosides (Acyclovir Sodium):
129. MOA of Purine Nucleosides (Acyclovir Sodium):
130. Side Effects of Purine Nucleosides (Acyclovir Sodium):
131. Adverse Reactions of Purine Nucleosides (Acyclovir Sodium):
132. MOA of Metronidazole (Flagyl):
133. Uses of Metronidazole (Flagyl):
134. Side Effects of Metronidazole (Flagyl):
135. Contraindications of Fluconazole (Antifungal: Azoles):
136. Interactions of Fluconazole (Antifungal: Azoles):
137. Uses of Fluconazole (Antifungal: Azoles):
138. MOA of Fluconazole (Antifungal: Azoles):
139. Side Effects of Fluconazole (Antifungal: Azoles):
140. MOA of Nystatin (Antifungal: Polyenes):
141. Uses of Amphotericin B (Antifungal Polyenes):
142. MOA of Amphotericin B (Antifungal Polyenes):
143. Side Effects of Amphotericin B (Antifungal Polyenes):
144. Adverse Reactions of Amphotericin B (Antifungal Polyenes):
145. Contraindications of Antitubercular (Isoniazid):
146. Interactions of Antitubercular (Isoniazid):
147. Uses of Antitubercular (Isoniazid):
148. Side Effects of Antitubercular (Isoniazid):
149. MOA of Antitubercular (Isoniazid):
150. Adverse Reactions of Antitubercular (Isoniazid):
151. Trade Name of Antitubercular (Isoniazid):
[Show More]
.png)
.png)
.png)
.png)
 - Georgia Southern University.png)
.png)
.png)
 (Q&A).png)
.png)
.png)
.png)
.png)
.png)
.png)
.png)
