Health Care > EXAM > ONS/ONCC Chemotherapy Immunotherapy Certificate Exam | 300+ Questions And Answers (All)

ONS/ONCC Chemotherapy Immunotherapy Certificate Exam | 300+ Questions And Answers

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ONS/ONCC Chemotherapy Immunotherapy Certificate Exam | 300+ Questions And Answers Define mutations - ANSWER- Variations in the nucleotide sequence of a gene 3 main goals of treatment... : - ANSWER- Cure Control Palliation Define neoadjuvant therapy - ANSWER- Treatment is given prior to surgery to shrink the tumor Define adjuvant therapy - ANSWER- Additional cancer treatment given after the primary treatment to lower the risk that the cancer reoccur Define conditioning/preparative therapy - ANSWER- Treatments used to prepare a patient for stem cell transplantation 2 types of conditioning therapies: - ANSWER- Myeloablative Nonmyeloablative Define dose density - ANSWER- Drug dose per unit of time Define dose intensity - ANSWER- Amount of drug delivered over time How is relative dose intensity (RDI) calculated? - ANSWER- By comparing the dose that the patient ACTUALLY received to the planned dose of the standard regimen How do alkylating agents work? - ANSWER- By causing a break in the DNA helix strand, interfering with DNA replication and causing cell death 3 subcategories of alkylating agents: - ANSWER- 1. Nitrogen mustards 2. Platinum-based agents (do not possess an alkyl group but still termed alkylating agents as they work similarly) 3. Nitrosoureas Most common subcategory of alkylating agents: - ANSWER- Nitrogen mustards Common alkylating agents: - ANSWER- Cyclophosphamide (Cytoxan) Ifosfamide (Ifex) Bendamustine (Treanda) Common platinum-based agents: - ANSWER- Cisplatin (Platinol) Carboplatin (Paraplatin) What is unique about nitrosoureas agents? - ANSWER- Able to cross the bloodbrain barrier; can be effective in treating some brain tumors Common nitrosoureas agents: - ANSWER- Carmustine (BiCNU) Lomustine (CeeNu) Streptozocin (Zanosar) Hypersensitivity can occur with late doses of: - ANSWER- Carboplatin These agents are typically categorized as highly emetogenic: - ANSWER- 1. Alkylating [Show More]

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