SBB 5261 Exam 1 Latest 2023 Rated A+

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SBB 5261 Exam 1 Latest 2023 Rated A+ IgG Sublcass most efficient in initiating classical complement ✔✔IgG3 Steric exclusion of water molecules is the mechanism of this enhancement ✔✔PeG Stage of Complement activation common to all three pathways ✔✔Activation Phase-C3 convertase IgM agglutination is enhanced at what temperature ✔✔Lower than RT Activation of C1 in classical pathway requires ✔✔Calcium What antigens are destroyed by Enzymes ✔✔MNSs Fya and Fyb A shot containing killed virus which causes the body to produce antibodies is what kind of immunity ✔✔Adaptive A shot containing gamma globulin is what kind of immunity ✔✔Passive Aquired The mechanism of cell death ✔✔Apoptosis The overall strength of binding between an antibody and antigen ✔✔Avidity The strength of the binding force between the FAB of an antibody with corresponding epitope ✔✔Affinity The stage of complement that causes cell lysis ✔✔Membrane Attack Phase AHG must contain what ✔✔IgG and C3d This immunoglobulin is found in both monomeric and polymeric forms ✔✔IgA What enhancement requires IgG to avoid non-specific reaction due to complement ✔✔PeG The deficiency of this Complement Component has been linked with recurrent life threatening infections ✔✔C3 The Complement regulatory protein that bind to C5b67 ✔✔CD59 What marker is found on stem cells and immature cells ✔✔CD34 What interluekin is required for the growth and differentiation of T cells to become effector T Cells ✔✔IL-2 The immunoglobulin isotype is determined by what ✔✔Constant region of heavy chain Complement Components that have anaphylactic activity ✔✔C3a and C5a A hybridoma is made by fusing a myeloma cell with what ✔✔B cells The main mechanism of action of Complement is ✔✔Facilitate recognition of phathogen Which Immunoglobulin shows parasitic infection and Hay fever ✔✔IgE What does Pepsin do to an immunoglobulin ✔✔Cuts the top from the bottom What does a thiol reagent do ✔✔breaks down to 2 light chains and 2 heavy chains What immunoglobulins are found on B lymphocytes ✔✔IgM and IgD What induces the differentiation of B cells to plasma cells ✔✔T cells Where is the hinge region on an immunoglobulin ✔✔CH1 and CH2 T Helper Cells ✔✔CD4 T Cells ✔✔CD8 Activates both cytoxic T cells and helper T cells ✔✔CD3 Decay Accelerating Factor ✔✔CD55 What part of complement does DAF (CD55) affect ✔✔Bb Activates vascular endothelium ✔✔IL-1 Growth of B cells, IgG and causes fever ✔✔IL-6 Activates macrophages and inducer of Class II MHC expression ✔✔IFNy neutrophil chemotactic factor and induces phagocytosis ✔✔IL-8 Immunoglobulins that Cross Placenta ✔✔IgG Immunoglobulins that fix complement ✔✔IgG and IgM Half Life of IgG ✔✔23 days Half Life of IgA ✔✔15 days Half Life of IgM ✔✔5 days Immunoglobulin that is predominant in secretions ✔✔IgA First Ig calss produces in immune response and found on B lymphs ✔✔IgM Type of Red Cell destruction that occurs within the blood cell that is life threatening with schistocytes and Neg DAT ✔✔Intravascular Type of Red Cell Destruction that occurs in spleen and liver, usually not life threatening with positive DAT and spherocytes ✔✔Extravascular What antibodies are found in Intravascular Red Cell Destruction ✔✔ABH, AntiPP, Vel, Lea, and Jka

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