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SBB Questions and Answers 100% Pass Chemicals that send signals between cells are ✔✔Cytokines Antibodies are made by what cells? ✔✔Plasma cells Where do B cells mature? ✔✔Bone Marrow Where do T cells mature? ✔✔Thymus ...

SBB Questions and Answers 100% Pass Chemicals that send signals between cells are ✔✔Cytokines Antibodies are made by what cells? ✔✔Plasma cells Where do B cells mature? ✔✔Bone Marrow Where do T cells mature? ✔✔Thymus Coating of a cell with antibodies or complement is called? ✔✔Opsonization CD4 + cells are? ✔✔T helper cells The specific chemical group that provokes an antibody response ✔✔Epitope Blood groups are made of two main kinds of chemicals ✔✔Proteins, carbohydrates What is the function of the FC piece of an immunoglobulin? ✔✔Monocyte binding What is the only Ig that crosses the placenta? ✔✔IgG What does 2-ME OR DTT do to IgM antibodies? ✔✔Destroys disulfide bonds Which is the secretory Ig? ✔✔IgA Which Ig is responsible for allergic reaction's? ✔✔IgE Which IgG subclass does not bind complement? ✔✔IgG4 Which IgG sub classes are most clinically significant? ✔✔IgG 1 & 3 What is isotype switching? ✔✔Example IgM switches to IgG What is the end point of complement activation? ✔✔Hole in cell At what stage of complement cascade is it amplified? ✔✔C3 activation What two ions are needed for complement activity? ✔✔Ca++ and Mg++ Name two complement components that are anaphylatoxins ✔✔C3a and C5a What is the minimum number of days a BBK specimen must be kept? ✔✔Seven days post transfusion Name two groups for which weak D testing is required ✔✔Donors, NB of D- Moms What is required for crossmatch specimen to be used longer than three days? ✔✔Known history, not pregnant or transfusion last three months What can be used to neutralize heparin? ✔✔Protamine sulfate If given Rh positive cells to Rh negative person, what does standards require? ✔✔A policy?(and a Rhig policy) Name three requirements for when blood must be irrradiated ✔✔TA-GVHD risk; blood relative; HLA-matched Why can't you use an EDTA specimen for Donath Landsteiner test? ✔✔It wouldn't lyse C' What is meant by thermal amplitude? ✔✔How high temp of reaction What is ZZAP? ✔✔Ficin OR papain AND DDT What concentration of albumin is used as a serum control?

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