Student’s Name
Institutional AffiliationSynopsis of Judy Pham's case
18 years old female.
CC: Urination frequency , urgency, pain, presence of
blood in urine.
Acute onset of symptoms.
fever, chills and vomi
...
Student’s Name
Institutional AffiliationSynopsis of Judy Pham's case
18 years old female.
CC: Urination frequency , urgency, pain, presence of
blood in urine.
Acute onset of symptoms.
fever, chills and vomiting are denied.
Social: movies, basket ball and partying .
Sexually active, one sexual; partner, unprotected sex.
Diagnosis: acute uncomplicated Cystitis, chlamydia.
Prescription: Nitrofurantoin and azithromycin.
Education: Abstain for one week after medication.HPI
18 years old.
Previously healthy.
Acute onset of urinary disorders.
Increased frequency, urgency (Alidjanov at al., 2016).
Painful urination and blood in urine.
Sexually active, admits unprotected sex.
Fever, vomiting, chills not reported.Medical History
Currently under no medication.
No history of major traumas and chronic disorders.
No allergies reported.
No medical intolerances.
No history of surgeries and hospitalization.Family History
Mother: No history chronic or acute disease.
Father: No history chronic or acute disease.
Sister: No history chronic or acute disease.Social History
Has taken marijuana once.
Admits alcohol but less frequently.
Denies tobacco and drug abuse.
Watches movies, basket ball and likes partying.
College student.
Stays in school dormitory.
Currently home for thanksgiving.
No safety concerns.ROS
General:
No chills and fever reported.
Skin:
No lesions, bruising and rushes.
HEENT:
No abnormalities reported.
Cardiovascular:
No chest pain, edema and palpitation reported.
Respiratory:
No wheezes, coughs and breathing difficulties reported.ROS cont…
Gastrointestinal: Non nausea, vomiting reported.
Musculoskeletal: Back pain denied.
Gynecological/genitourinary: Reports:
urination frequency, urgency, pain
presence blood in the urine
white vaginal discharge
Denies menstrual abnormalities
Reports recent unprotected sex.
Denies pain during sexual intercourse.Examination
Vital sign:
P: 88 b/min, BP: 92/55 mmHg, T: 97.2 F, R: 16 b/min.
H: 160 cm, W: 105 llbs, BMI: 18.6 kg/m2.
General:
Healthy, no acute distress.
Cardiovascular:
No murmurs.
Respiratory:
Lungs clear to auscultation.
Skin:
No lesions.Examination cont…
Back:
No costovertebral angle tenderness.
Gastrointestinal:
Stomach soft on touch,
normal active bowel sounds,
mild midline suprapubic tenderness,
Non-distended bladder.
Pelvic:
No redness, ulceration,
No skin, labia and introitus, abnormalities.
Small amount of white discharge.
Normal looking cervix.Labs
Pregnancy Test:
Negative
Pelvic exam:
Whiff-amine test : negative
Two to five white cells per high-power field
Vaginal discharge: Hp is 4.0.
Urine deep stick (Alidjanov at al., 2020):
Positive for nitrites, leukocyte esterase and hemoglobinDiagnosis
Primary Diagnosis:
Acute uncomplicated Cystitis:
Acute onset of symptoms (Alidjanov at al., 2016).
Urination frequency, urgency, blood in urine.
Dysuria and hematuria.
Physical exam and lab findings supported diagnosis.
Differential Diagnosis:
Cervicitis with urethritis.
Pelvic inflammatory disease.
Pyelonephritis.Treatment Plan
Medication:
Nitrofurantoin. Dose intervals: 100 mg q 12 hours. Duration: 5
days (Aliaga at al., 2017)
azithromycin
Non-medication treatment: None given.
Tests ordered:
Pelvic exam, urine deep stick, pregnancy test.
Education:
Abstain from sex from one week after medication.
Ask boy friend to get treated for Chlamydia.
Follow-up:
Collect azithromycin from the pharmacy and collect HIV test
results.
Referral: None.Evidence-based Articles
Prevention of Recurrent Acute Uncomplicated Cystitis by
Increasing Daily Water in Premenopausal Women by
Hooton and collegues 2017.
This article was written following a study to assess how
increased daily water intake can help prevent reoccurrence
of acute uncomplicated Cystitis.
The results of the study revealed that increase in the intake
of water was efficient in preventing recurrent acute
uncomplicated cystitis by 48% and antimicrobial regimens
by 47%.
Ms Pham should have been advised to increase daily water
intake to prevent recurrent of Acute Uncomplicated
Cystitis.Evidence-based Articles cont…
Preferential Use of Nitrofurantoin Over Fluoroquinolones for
Acute Uncomplicated Cystitis and Outpatient Escherichia
coli Resistance in an Integrated Healthcare System by Pedela
and colleagues 2017.
This article evaluates changes in the n fluoroquinolone and
nitrofurantoin in patients with acute uncomplicated cystitis.
It also evaluates changes in resistance among E.
coli isolates after institutional guidance recommended use of
nitrofurantoin over fluoroquinolone in patients with acute
uncomplicated cystitis.
The authors concluded that reduction in the use of
Fluoroquinolones caused the change in institutional
guidance for acute uncomplicated cystitis resulting in
stabilization in FQ-resistant E. coli.
They also concluded that increases use of Nitrofurantoin was
not associated with changes in Nitrofurantoin resistance.Evidence-based Articles cont…
MP71-10 THE DIAGNOSTIC VALUES OF SYMPTOMS FOR
ACUTE UNCOMPLICATED CYSTITIS – EVALUATION OF THE
PROPOSED UPDATED FDA GUIDELINES by Alidjanov and
colleagues 2019.
This article reevaluates the diagnostic values of the symptoms of
acute uncomplicated cystitis using ACSS score.
After the evaluation, the authors concluded that: s
Severity of symptom rather than their presence is essential for
accurate diagnosis of acute cystitis.
Dysuria has the highest diagnostic value of the symptoms and
Incomplete bladder empting should also be added to the
symptoms.
ACSS is a useful tool in the diagnosis of acute cystitis.
This article is applicable in Ms Pham’s case since she was
diagnosed with acute uncomplicated cystitis.Evidence-based Articles cont…
Green tea as an adjunctive therapy for treatment of acute
uncomplicated cystitis in women by Kheirabadi and colleagues
2019.
This article evaluate the efficacy of green tea as an adjunctive
therapy to standard treatment of women with acute
uncomplicated cystitis.
A study was conducted and the results revealed:
Significant decrease in symptoms of cystitis
Significant improvement in the urinalysis results
No improvement for hematuria.
Authors concluded that green tea is an effective suppliment
when used with trimethoprim–sulfamethoxazole to treat acute
uncomplicated cystitis.
If trimethoprim–sulfamethoxazole was prescribed in Pham’sd
case, green tea suppliment could have been recommended.Evidence-based Articles cont…
Screening for genital Chlamydia infection by Low and
colleagues 2016.
This article examines the effects and safety Chlamydia
screening versus standard care on Chlamydia
infection.
It follows a study whose results revealed that:
Detection and treatment of Chlamydia infection can
reduce the risk of PID.
This article related to Pham’s case since she was also
diagnosed with Chlamydia.References
Aliaga, L., Moreno, M., Aomar, I., Moya, S., & Ceballos, Á. (2017). Treatment of Acute
Uncomplicated Cystitis. A Clinical Review. Int J Fam Commun Med, 1(2), 00009.
Alidjanov, J. F., Abdufattaev, U. A., Makhsudov, S. A., Pilatz, A., Akilov, F. A., Naber, K.
G., & Wagenlehner, F. M. (2016). The acute cystitis symptom score for patient-reported
outcome assessment. Urologia internationalis, 97(4), 402-409.
Alidjanov, J. F., Naber, K. G., Pilatz, A., Radzhabov, A., Zamuddinov, M., Magyar, A., ... &
Wagenlehner, F. M. (2020). Evaluation of the draft guidelines proposed by EMA and
FDA for the clinical diagnosis of acute uncomplicated cystitis in women. World journal
of urology, 38(1), 63-72.
Hooton, T. M., Vecchio, M., Iroz, A., Tack, I., Dornic, Q., Seksek, I., & Lotan, Y. (2017).
Prevention of recurrent acute uncomplicated cystitis by increasing daily water in
premenopausal women: A prospective, randomized, controlled study. In Open forum
infectious diseases (Vol. 4, No. suppl_1, pp. S736-S736). US: Oxford University Press.
Kheirabadi, Z., Mehrabani, M., Sarafzadeh, F., Dabaghzadeh, F., & Ahmadinia, N. (2019).
Green tea as an adjunctive therapy for treatment of acute uncomplicated cystitis in
women: A randomized clinical trial. Complementary therapies in clinical practice, 34, 13-
16.
Low, N., Redmond, S., Uusküla, A., van Bergen, J., Ward, H., Andersen, B., & Götz, H.
(2016). Screening for genital chlamydia infection. Cochrane Database of Systematic
Reviews, (9).
Pedela, R. L., Shihadeh, K. C., Knepper, B. C., Haas, M. K., Burman, W. J., & Jenkins, T.
C. (2017). Preferential use of nitrofurantoin over fluoroquinolones for acute
uncomplicated cystitis and outpatient Escherichia coli resistance in an integrated
healthcare system. infection control & hospital epidemiology, 38(4), 461-468.
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