WGU D027 Practice Test Questions and answers, rated A+. verified.

WGU D027 Practice Test Questions and answers, rated A+. verified. A patient has endured several dosage adjustments of his tricyclic antidepressant, so the provider recommends genetic testing. Which statement correct ...

WGU D027 Practice Test Questions and answers, rated A+. verified. A patient has endured several dosage adjustments of his tricyclic antidepressant, so the provider recommends genetic testing. Which statement correctly describes the rationale for genetic testing? a. The CYP2D6 gene influences metabolism of tricyclic antidepressants and certain other drugs. b. The HER2 gene is a tumor marker that impacts metabolism of tricyclic antidepressants. c. The BRCA2 gene influences metabolism of certain drugs and increases the risk for breast cancer. d. The x linked OPN1MW gene for male color blindness also slows metabolism of certain - ✔✔-a. The CYP2D6 gene influences metabolism of tricyclic antidepressants and certain other drugs. HER2 is a gene often implicated with cancer, as is BRCA2. OPN1MW is the gene that codes for color blindness in men. Metabolism of 25% of all prescribed drugs, including tricyclic antidepressants, beta adrenergic receptor blockers, and neuroleptics, is influenced by variants in a certain gene, requiring genetic testing to reduce trial-and-error in estimating appropriate drug-dosage levels. According to the Centers for Disease Control and Prevention, the 10 most costly chronic conditions include cardiovascular diseases, obesity, asthma, diabetes, smoking and alcohol related conditions, cancer, Alzheimer's disease, arthritis and stroke. Which are the top 4 in ranking from most costly to least costly? a. Cardiovascular diseases, obesity, diabetes, cancer b. Cardiovascular diseases, diabetes, obesity, cancer c. Cardiovascular diseases, Smoking-related conditions, Alcohol-related conditions, diabetes d. Cardiovascular diseases, Stroke, Obesity, Diabetes - ✔✔-c. Cardiovascular diseases, Smoking-related conditions, Alcohol-related conditions, diabetes A mother brought her child to the doctor for genetic testing. The health care provider was trying to explain the genetic results of the child. During his explanation he tells the mother that the child has 2 X chromosomes and a Y chromosome in each cell. He begins to explain some physical appearances the mother might notice on her son. He explains that she might notice that he has sparse body hair, long limbs and small testes. The health care practitioner is explaining which syndrome to the mother. a. Klinefelter syndrome b. Turners' syndrome c. Down syndrome d. Kawasaki's disease - ✔✔-a. Klinefelter syndrome Klinefelter syndrome is an individual with at least 2 X chromosomes and a Y chromosome in each cell. Because of the Y chromosome these individuals have a male appearance, but they are usually sterile and about half develop female-like breasts. A patient reports a maternal family history of Lynch syndrome. Which laboratory finding might indicate a need for further testing for the presence of Lynch syndrome in this patient? a. Elevated thyroid-stimulating hormone b. Low cortisol level c. Positive heme-occult test d. Sputum positive for Pseudomonas Aeruginosa - ✔✔-a. Positive heme-occult test Positive heme-occult because Lynch syndrome is a hereditary form of colorectal cancer and colorectal bleeding can be a sign of cancer An individual's acquired immunity is dependent on the function of which cells? (Select all that apply.) a. B lymphocytes b. Opsonins c. T lymphocytes d. Macrophages - ✔✔-a. B lymphocytes c. T lymphocytes d. Macrophages T lymphocytes, B lymphocytes, macrophages, and dendritic cells are involved in acquired immunity. A 17-year-old female comes to the clinic for a physical exam. As part of the visit, the APRN considers her risk factors for type 2 diabetes mellitus (T2DM). Risk factors for T2DM would likely include all of the following except: a. Native American ancestry b. Family history of type 1 diabetes mellitus (T1DM) c. Obesity d. Personal history of polycystic ovary syndrome (PCOS) - ✔✔-b. Family history of type 1 diabetes mellitus (T1DM) Type 1 diabetes has the genetic link and is something they are born with Some older adults have impaired inflammation and wound healing because of which problem? a. Circulatory system cannot adequately perfuse tissues. b. Complement and chemotaxis are deficient. c. Underlying chronic illness(es) exists. d. Number of mast cells is insufficient. - ✔✔-c. Underlying chronic illness(es) exists. A patient is diagnosed with chronic obstructive pulmonary disease (COPD) and has elevated pulmonary vascular resistance. Which symptom would indicate the need to assess for the complication of cor pulmonale (right-sided heart failure)? a. crackles bilaterally b. generalized arthralgia c. jugular venous distention d. occasional constipation - ✔✔-c. jugular venous distention Symptoms of right-sided heart failure include the following: hepatosplenomegaly, extremity edema, ascites, jugular venous distention A parent asks the healthcare professional to explain why a child diagnosed with Tetralogy of Fallot squats often. What explanation by the professional is best? a. It helps to alleviate chest pain b. Relieves hypoxia c. Controls vertigo d. Improves constant headaches - ✔✔-b. Relieves hypoxia Squatting is a spontaneous compensatory mechanism used by older children with Tetralogy of Fallot to alleviate hypoxic spells. Squatting and its variants increase systemic resistance while decreasing venous return to the heart from the inferior vena cava. A patient who has lung cancer reports facial and neck swelling so severe that some shirts no longer fit. What question by the healthcare professional would be most appropriate to screen for superior vena cava syndrome, a possible complication of cancer tumors? a. "Have you gained weight recently?" b. "Are your feet and ankles swollen?" c. "Does your voice sound hoarse?"