NCLEX 101 ATI Final 2020 – Rasmussen College | NCLEX101 ATI Final 2020

NCLEX 101 ATI Final 2020 – Rasmussen College CLASS PROTOTYPE ACTION USES SIDE EFFECTS INTERACTIONS NI AFFECTING NSAIDS NSAIDS: Asprin2nd Gen: Celecoxib (celebrex) decrease inflammation, pain, and fever Inflam ...

NCLEX 101 ATI Final 2020 – Rasmussen College CLASS PROTOTYPE ACTION USES SIDE EFFECTS INTERACTIONS NI AFFECTING NSAIDS NSAIDS: Asprin2nd Gen: Celecoxib (celebrex) decrease inflammation, pain, and fever Inflammation, Analgesia, fever reduction, dysmenorrhea GI discomfort, gastric ulcers, bleeding, Renal dysfunction, Salicylism, Reye Syndrome Warfarin, Clucocorticoids, Alcohol, Ibuprofen Take with food, milk, or fully glass of wather Pain and inflammation Antigout Colchicine decrease inflammation Gout GI toxicity Warfarin Pain and inflammation Migraine Medications Ergot alkaloids: Ergotamine(ergostat)Serotonin receptor agonists (Triptains): Sumatripitan (Imitrex) prevent inflammation and dilation to intracranial blood vessels abort acute migraine attack, prevent migraines Ergot: GI discomfort;Ergotism, physical dependence, abortionTriptans: Chest symptoms, angina, teratogenic Triptains with MAOI's Avoid trigger factors. Pain and inflammation Opiod Antagonist Naloxone (Narcan) interfere with the action of opioids opioid overdose, reverse effects of opioids, reversal of resp. depression in infants tachycardia, tachypnea, abstinence syndrome Pain and inflammation Neuromuscular Blocking Agents Nondepolarizing: Tubocurarine (Tubarine) Depolarizing:succinylcholine (Anecitine) Block ACh at neruomuscular junction adjuncts to general anesthesia, diagnosis myasthenia gravis, seizure control, endotracheal intubation, endoscopy Respiratory arrest, hypotentionSuccinylcholine: apnea, malignant hypertention, hyperkalemia General anesthetics, Aminoglycosides, tetracyclines, Cholinesterase inhibitors continuous cardiac monitoring Nervous system - - - - - - - - - - - - - - - Penicillins penicillin G (Bicillin LA) weakening the bacterial cell wall meningitis, syphilis, prophylaxis bacterial endocarditis Allergies, renal impairment,hyperkalemia Aminoglycosides, OC full glass of water 1 hr before meals or 2 hr after Infection Cephalosporins cephalexin (Keflex)cefaclor (Ceclor)ceftriaxone(Rocephin)cefepime(maxipime destroy bacterial cell wall UTI, postoperative infection, pelvic infection, meningitis Allergice, bleeding, thrombophlebitis, cross allergy disulfiram reaction, probenecid take with food Infection Carbapenems imipenem (Primaxin) destroy cell wall pneumonia, peritonitis, UTI allergy, GI symptoms, Suprainfection Infection Monobactams Vancomycin (Vancocin) destroy cell wall serious infections ototoxicity, infusion reaction, thrombophlebitis Infection Tetracyclines tetracycline hydrochloride (sumycin) inhibit growth rickettsia, acne vulgaris GI discomfort, yellow/brown tooth discoloration, hepatotoxicity, photosensitivity, suprainfecrtion Milk products, iron, magnesium,antacids, OC dont give with food Infection Bacteriostatic inhibitors erthyromycin (E-mycin) slows growth treat clients with penicillin allergy, whooping cough GI discomfort, thrombophlebitis Antihistamines, theophylline, warfarin empty stomach infection Aminoglycosides gentamicin (Garamycin) disrupt protein syntesis tapeworm Ototoxicity, nephrotoxicity, neuromuscular blockade penicillin peak and trough infection Sulfonamides and trimethoprim trimthoprim-sulfamethoxazole(TMP-SMZ, Bactrim) inhibit bacterial growth UTI hypersensitivity,blood dyscrasias, kernicterus(jaundice, increase bili), photosensitivity warfarin, phenytoin, slufonylurea empty stomach, full glass of water Infection Urinary Tract Antispeptics nitrofurantoin (macrodantin) damages DNA UTI GI discomfort, Hypersensitivity reactions, blood dyscrasias, peripheral neruopathy urine will have brownish discoloration Infection Antimycobacterial (Antituberculosis) isoniazid(INH) ihibits growth of mycobacteria, prevents synthesis ofmycolic acid TB peripheral neuropathy, hepatotoxicity phenytoin, Alcohol empty stomach Infection Anti-hansens disease dapsone prevents synthesis of folic acid treatment of hansens disease discoloration of body fluids, hepatoxicity, mild GI discomfort warfarin, OC,protease inhibitors complete course infection Antiviral acyclovir(Zovirax) prevents reproduction of viral DNA herpes simplex virus, HIV phlebitis and inflammation at site, nephrotoxicity, mild GI discomfort, Granulocytopenia and thrombocytopenia, reproductive toxicity never administer bolus, IV over 1 hour Infection Fluoroquinolones ciprofloxacin(Cipro) inhibition of enzyme necessary for DNA replication severe infections, resp, urinary, and GI infections GI discomfort, Achilles tendon rupture, suprainfection, Cationic compounds, theophylline, warfarin Infection Antiprotozoals metronidazole(flagyl) slows growth peptic ulcer disease, protozoal infections GI discomfort, metallic taste, darkening of urine, CNS symptoms alcohol, metronidazole complete course infection Antifungal amphotericin B deoxycholate(fungizone) acts on fungal cell membranes to increase cell permeability fungal infections, dermatophytic infections Infusion reaction, thrombophlebitis, nephrotoxicity, hypokalemia, bone marrow suppression Aminoglycosides, flucytosine Infection Acetaminophen acetaminophen (Tylenol) slows production of prostaglandins Analgesic, antipyretic Acute toxicity Alcohol, Warfarin Pain and inflammation Opioid Agonists Morphine sulfate act of mu receptors moderate to severe pain, sedation, reduction of bowel motility, Codiene: cough suppression Respiratory depression, constipation, orthostatic hypotention, urinary retention, sedation, biliary colic, emesis, opioid overdose triad CNS depressants, Anticholinergic agents, MAOI's, Antihypertensives withhold if R<12, IV slowly (4-5 min) Pain and inflammation Agonists-Antagonist Opioids Pentazocine (Talwin) low potential for abuse, less respiratory depression. Antagonist to mu receptors, agonist to kappa receptors mild to moderate pain Abstinence syndrome NONE withhold if R<12 Pain and inflammation Cholinesterase inhibitors neostigmine (Prostigmin) "mine" increase amount of ACh available at receptor sites Myasthenia gravis, reversal of neuromuscular blocking agents increase GI motility and secretions; Cholinergic crisis, bradycardia, urinary urgency Atropine, tubocuraine, Succinylcholine medical alert bracelet Nervous system