*NURSING > CASE STUDY > Walden UniversityNURS 6501NURS6501Wk10Assgn-Sepsis (All)
Walden UniversityNURS 6501NURS6501Wk10Assgn-Sepsis
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Eitiology Leading cause of death in the U.S. Cost of treating sepsis exceeds $17billion annually Pathophysiology Endotoxin introduced to host Triggers release of CD4 cells whic... h release: Anti-inflammatory cytokines Tumor necrosis factor, interluekons 1,2,6,8,12 ,y and platlett aggregating factor This activates the: Hypothalmus-fever, increased heart rate and respiratory rate Capillary Endothelial Cell-neutrophil margination, platelet adherence, DIC and depletion of intravascular volume Vessel Wall-Vasodilitation The activation of the endothelial cell and the vessel wall precipitate cellular hypoxia which leads to lactic acidosis [Show More]
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