A nurse working for a drug company is involved in phase III drug
evaluation studies. Which of the following might the nurse be responsible
for during this stage of drug development?
Selected
Answer:
D.
Monitoring d
...
A nurse working for a drug company is involved in phase III drug
evaluation studies. Which of the following might the nurse be responsible
for during this stage of drug development?
Selected
Answer:
D.
Monitoring drug effects in patients who are selected to
participate in a study, who have the disease that the drug is
meant to treat
Correct
Answer:
C.
Administering investigational drugs to patients
Response
Feedback
:
Phase III studies involve administering investigational drugs to
patients in a vast clinical market who are voluntarily enrolled in
double-blind studies. In phase I studies, a small number of
healthy human volunteers are given the drug after blood urine
and other appropriate samples are taken to monitor drug
metabolism. Sometimes volunteers who have a certain disease
are used in phase I instead of healthy volunteers if the drug is
expected to have significant toxicity. In phase II, volunteers are
given various dosages of the test compound and studied in great
detail. Dosage guidelines are usually determined in this phase.
Nurses are more likely to be responsible for administering the
investigational drugs in phase III than in phases I and II. Use of
animal testing is done in the preclinical trials and would not
involve a nurse.
Question 2
0 out of 1 points
A nurse is caring for a 46-year-old patient of Chinese origin who has
bipolar disorder. The physician has prescribed lithium carbonate (Eskalith)
to treat the disorder. The nurse is aware that the lithium dose will likely be
given in a
Selected
Answer:
D.
higher-than-normal
dose.
Correct
Answer:
C.
lower-than-normal
dose.
Response
Feedback
:
The patient would likely be prescribed a lower-than-normal dose
of lithium to treat the disorder since he is an American. Chinese
Americans require lower levels of lithium to achieve a
therapeutic response. Different drugs can be metabolized only
by specific liver enzymes, and receptors are custom-designed to
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