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Introduction to Neuroscience 2100 (Campeau)

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How are neurotransmitters deactivated when they are released in the synapse (hint: there are 2 different mechanisms)?  Reuptake into presynaptic terminals or glial cells (ex. Amino acids-excitato ... ry amino acid transporters)  Enzymatic degradation (ex. Acetylcholinestrase- AChE) What determines the effects of specific neurotransmitters (hint: it is NOT the neurotransmitter molecules)?  Postsynaptic receptors determine the effects of neurotransmitters. What are neurotransmitter receptors?  A membrane receptor protein that is activated by a neurotransmitter. What are different subtypes of NT receptors?  Catecholaminergic o Dopamine o Norepinephrine o Epinephrine  Amino Acidergic o Serotonin  Cholinergic o Nicotinic, Muscarinic  Glutamatergic o AMPA,  Selective to Na+ o NMDA,  Na+ K+ o Kainate o mGluR  Serotonergic What are the different major types of NT receptors? (hint: we described two major types in class, but we discussed a total of 4 major types)  Inotropic  Metabotropic  Enzyme-Linked  Intracellular [Show More]

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