Contains USMLE Sample Test Questions:
Brief examples:
1.
A 67-year-old woman with congenital bicuspid aortic valve is admitted to the hospital because of a 2-day history of
fever and chills. Current medication is l
...
Contains USMLE Sample Test Questions:
Brief examples:
1.
A 67-year-old woman with congenital bicuspid aortic valve is admitted to the hospital because of a 2-day history of
fever and chills. Current medication is lisinopril. Temperature is 38.0°C (100.4°F), pulse is 90/min, respirations are
20/min, and blood pressure is 110/70 mm Hg. Cardiac examination shows a grade 3/6 systolic murmur that is best
heard over the second right intercostal space. Blood culture grows viridans streptococci susceptible to penicillin. In
addition to penicillin, an antibiotic synergistic to penicillin is administered that may help shorten the duration of this
patient's drug treatment. Which of the following is the most likely mechanism of action of this additional antibiotic
on bacteria?
(A) Binding to DNA-dependent RNA polymerase
(B) Binding to the 30S ribosomal protein
(C) Competition with p-aminobenzoic acid
(D) Inhibition of dihydrofolate reductase
(E)Inhibition of DNA gyrase
2.
A 12-year-old girl is brought to the physician because of a 2-month history of intermittent yellowing of the eyes and
skin. Physical examination shows no abnormalities except for jaundice. Her serum total bilirubin concentration is
3 mg/dL, with a direct component of 1 mg/dL. Serum studies show a haptoglobin concentration and AST and ALT
activities that are within the reference ranges. There is no evidence of injury or exposure to toxins. Which of the
following additional findings is most likely in this patient?
(A) Decreased activity of UDP glucuronosyltransferase
(B) Gallstones
(C) Increased hemolysis
(D) Increased serum alkaline phosphatase activity
(E) Ineffective erythropoiesis
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