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SCIENCE 101 > QUESTIONS & ANSWERS > Neuroscience - Membrane Permeability 2 (All)

Neuroscience - Membrane Permeability 2

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Voltage-Dependent Membrane Permeability 2 Questions & Answer 1. Which of the following is not integral to the action potential waveform? a. A change in permeability of the membrane to sodium b. A ... change in permeability of the membrane to potassium c. A transient increase in the sodium current d. An initial decrease in the potassium current e. A “self-activating” aspect to the rise in the sodium current Answer: d Textbook Reference: Overview 2. For which reason was the development of the voltage clamp critical to investigations of the ionic basis of the action potential? a. Voltage changes in the cell cannot be seen without voltage clamp. b. Ionic conductances can be activated only in cells that have been voltage clamped. c. Voltage clamping allows simultaneous control of membrane potential and measurement of permeability changes. d. Sodium and potassium currents are activated in non-overlapping voltage regimes. e. Voltage clamping does not require specialized equipment. Answer: c Textbook Reference: Ion Currents across Nerve Cell Membranes 3. Which observation was not observed in Hodgkin and colleagues’ voltage-clamp study of squid action potentials? a. Capacitive currents in response to hyperpolarizing voltage steps b. Capacitive currents in response to depolarizing voltage steps c. A transient inward current as a result of depolarization d. A sustained outward current as a result of hyperpolarization e. A delayed outward current as a result of depolarization Answer: d [Show More]

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