BioChem C785 - WGU - Module 1 - all
Questions and Correct Answers Rated
A+
A couple has 6 children, 4 girls and 2 boys, all of whom have prominent chin dimples. If only the
mother has a prominent chin dimple, what is
...
BioChem C785 - WGU - Module 1 - all
Questions and Correct Answers Rated
A+
A couple has 6 children, 4 girls and 2 boys, all of whom have prominent chin dimples. If only the
mother has a prominent chin dimple, what is the likely inheritance pattern for the chin dimple?
Correct Answer- autosomal dominance
A man and woman with both type O blood have 4 children, what will be the blood types of their
children? Correct Answer- 100% type O
A patient with xeroderma pigmentosum is prone to developing multiple skin cancers starting in
childhood. This occurs because of a mutation in a gene that codes for enzymes that help repair
DNA damage through the nucleotide excision repair (NER) pathways. How does the NER differ
from other repair mechanisms? Correct Answer- The error in one strand of DNA is removed as
well as several nucleotides on either side of the error. The gap that was removed is filled in by
DNA polymerase.
A research scientist is trying to create a new strain of bacteria that can produce a protein
needed for her research. What molecule will act as a template in creating the new protein?
Correct Answer- messenger RNA (mRNA)
A woman is homozygous for an abnormal gene on Chromosome 2 that codes for an autosomal
dominant disease. This means that she Correct Answer- will have the disease
An inherited autosomal recessive disease Correct Answer- can only occur if both parents carry
at least one abnormal gene
Blood is what type of inheritance? Correct Answer- codominanceDNA polymerase is involved in DNA replication. DNA polymerase Correct Answer- adds
nucleotides to the new NDA strand in the 5'-3' direction
DNA replication is semiconservative, which allows each of the 2 strands to serve as a template
for the new strands Correct Answer- true
Epigenetics: access to the promoter region of a gene by transcription factors is affected,
environmental stimuli control gene expression, and gene expression is influenced by chemical
modifications of the DNA and/or histone proteins Correct Answer- True
Hemophilia is an x-linked recessive condition Correct Answer- a person with at least one normal
X chromosome without the hemophilia gene will not show signs of hemophilia
Histone proteins can be chemically modified by addition of methyl group. As a result,
nucleosomes pack tightly and the process of transcription is decreased at those DNA sites
Correct Answer- True
How many amino acids, and which ones, would be encoded by the following mRNA sequence:
5'- AUGACUCCCGGG -3' Correct Answer- 4: MET, THR, PRO, GLY
In Kevin's case, a specific kind of mutation in the opsin gene resulted in the premature
termination of the translation process. This resulted in shorter opsin protein than usual. What
specific mutation could have caused this? Correct Answer- Nonsense mutation
Maternal smoking during pregnancy is hazardous yet common in many places. Many studies
have associated prenatal smoking to unhealthy physical and psychological outcomes for the
baby. Researchers know that maternal smoking affects are epigenetic in nature. Which event
can be considered epigenetic in nature? Correct Answer- Changes in chromatin structure
Mutation to the DNA strand that consists of a nucleotide sequence: 5'- CTG ACG TAT CTT AAT -
3' Correct Answer- 5'- CTG ACG TAA CTT AAT-3'One strand of chromosome 2 has a DNA sequence that consists of: 5'- AAG CGG TAC GTA -3'.
What will be the sequence of the complementary DNA strand? Correct Answer- 5' - TAC GTA
CCG CTT -3'
Promoters are DNA sequences near the start of a gene that are recognized by transcription
factors which recruit RNA polymerase to that gene for expression. This is an important aspect
of transcriptions but not part of the mRNA processing. Correct Answer- true
Recall that the DNA polymerase must bind a double-stranded polymer before it can start
making its own DNA polymer. What helps the DNA polymerase to overcome this problem in
DNA replication? Correct Answer- RNA primers
Red green colorblindess Correct Answer- is due to a mutation in the opsin gene
RNA nucleotides include the bases A, U, C, and G. RNA is single stranded and contains a ribose
sugar in the sugar-phosphate backbone. There are several types of RNA in the cell, including
mRNA, rRNA, and tRNA Correct Answer- true
Several components of cigarette smoke, including benzopyrene, insert themselves into the DNA
and lead to several types of mutations such as frameshift mutations, including both insertions
and deletion. Which repair pathway would be used to repair this type of damage? Correct
Answer- Nucleotide Excision Repair
Steps in the (BER) base excision repair: Correct Answer- 1. Removal of the damage by excising
part of one strand to leave a gap
2. Ligation to restore continuity of the DNA backbone
3. Recognition of the damage
The DNA sequence is 3'-ATGATCCTT-5' is part of the template strand during DNA replication.
What is the correct sequence for the newly made DNA? Correct Answer- 5'-TACTAGGAA-3'The gene for blue opsin protein is located on chromosome 7, a non-sex chromosome. What
kind of inheritance pattern would you expect to see with color blindness due to mutate blue
opsin? Correct Answer- an equal distribution of color blindness between males and females
The LCT gene codes for Lactase, which is responsible for the breakdown of lactose. How is the
Lactase activity increased? Correct Answer- the presence of lactose causes nucleosomes to
separate, exposing the LCT gene
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