CFRN Cardiac practice test
Vasopressors - ans-Low beta properties
Inhibits NO (methylene blue)
Profound neurogenic shock
Push dose pressors
Vasogenic shock
Refractory septic shock
Phenylephrine - ans-Pure
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CFRN Cardiac practice test
Vasopressors - ans-Low beta properties
Inhibits NO (methylene blue)
Profound neurogenic shock
Push dose pressors
Vasogenic shock
Refractory septic shock
Phenylephrine - ans-Pure alpha - increased BP without tachycardia
Causes increased aortic root pressure and CPP
Vasogenic shock with tachycardia , sepsis, neurogenic shock
10-100mcg/min load with drip rate 40-60mcg/min
Can cause reflexive bradycardia
Vasopressin - ans-Used for refractory shock when high doses of catecholamines are present
Releases catecholamine receptors
0.01-0.04u/min
Methylene blue - ans-Inhibits NO - causing vasoconstriction
Vasodilatory shock, septic shock
0.4-2mg/kg over 20min-1hour
Hydralazine - ans-Direct arterial vasodilator reducing afterload
HTN
5-10mg q 20 minutes
Drops both SBP/DBP
Nitroglycerin - ans-Dilates venous system reducing preload
Dilates arterial system in high doses
Relieves vasospasm
Angina
MI
LVF
Coronary artery spasm
0.4mg SL q5 min
5mcg/min -200mcg/min titrated q3-5 minutes by 5-20mcg/min
Nitroprusside - ans-Relaxes vascular smooth muscle
Dilates arterial and venous reducing after and preload
HTN w/ serious complications
LVF
Cardiogenic Shock
Aortic dissection
Watch for cyanide toxicity
0.5 - 10mcg/kg/min titrated q 5minutes
Heparin - ans-Accelerates formation of antithrombin III inactivating thrombin and preventing conversion of fibrinogen to fibrin
Blood clots
Caution in recent major surgery, ulcer, GIB, renal dysfunction
60-80u/kg bolus (max 5000u)
15-18u/kg/hr (max 1000u/hr)
Aggrastat - ans-IV glycoprotein IIB/IIIA platelet inhibitor
ACS/MI
Active bleeding, recent surgery
Load - 0.4mcg/kg/min over 30 minutes
Maintenance - 0.1mcg/kg/min over 12 hours
t-PA - ans-ischemic stroke:
0.9mg/kg (max 90mg)
First 10% over 1 minute
Remaining 90% over hour
STEMI
<67kg
15mg bolus over 1-2 minute
0.75mg/kg over 30 minutes
0.5mg/kg over next 60 minutes (max 35mg)
max total dose 100mg
>67mg
15mg over 1-2 minutes
50mg over 30 minutes
35mg over next 60 hours
PE
100mg over 2 hours
Followed by heparin infusion
Class 2 antidysrhythmics - ANS-This class of antidysrhythmics includes beta blockers like carvedilol, labetalol, propanolol (causes bronchoconstriction), timolol, esmolol, metoprolol.
These medications bind to the beta-adrenoreceptor blocking the binding of norepinephrine and epinephrine which inhibits sympathetic effects.
Cardiac index - ANS-normal: 2.5 - 5 L/min
Pulmonary vascular resistance (PVR) - ANS-measures afterload of the RIGHT heart
Normal: 50-250 dynes
Increase in PVR - ANS-caused by acidosis, hypercapnia, hypoxia, actelectasis, ARDS
Decrease in PVR - ANS-caused by alkalosis, hypocapnia, vasodilating drugs
Systemic vascular resistance (SVR) - ANS-Normal: 800-1200 dynes
Increase in SVR - ANS-Can be caused by vasoconstriction due to hypothermia, decreased cardiac output, hypovolemic shock, aftermath of pressors
Decrease in SVR - ANS-Can be caused by vasodilation due to anaphylaxis, neurogenic shock or septic shock, vasodilating drugs like nitroprusside, nitroglycerine, hydralazine.
Heart sounds - ANS-Due to valves opening and closing.
*"Toilet paper my arse" - tricuspid, pulmonic, mitral, aortic
S3 - ANS-"Ken-tuck- ee"
Heart sound that can be due to fluid overload.
Usually occurs due to overfilling of the left ventricle, CHF, choridae tendonae dysfunction
S4 - ANS-"Tenn-ee-ssee"
Usually due to a weak left ventricle, cardiomyopathy, hypertension or infarction (MI).
You would expect to hear this heart tone from a patient with a history of an old MI
How do you treat hyperkalemia? - ANS-IV insulin, D50, Kayexelate
* if your monitor is double counting your QRS or T waves it may indicate hyperkalemia and you may need to administer calcium
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