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ATI Pharmacology Study Guide.

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Absorption: How quickly or how well a medication is absorbed depends on the route. - Oral: more slowly, depends on food in stomach, pH of gastric content. Liquid absorbs more quickly than extended r ... elease - Sublingual: Absorbed more quickly, placed under the tongue. Mucosa under tongue is very vascular. Do not eat or drink until medication is completely absorbed. - Inhalation: Absorption happens very quickly. - Intradermal/topical: Absorption is slower. Lidocaine patch: slow steady release. - Subcutaneous/intramuscular: Absorption depends on the solubility of the medication and the blood perfusion at site - IV: absorption happens immediately Distribution: After absorption. Medication travels to the site of action. Medications need binding proteins in order to be distributed to travel to site. Albumin is a common protein used to bind, if pt.’s levels are low, will impact medication distribution. [Show More]

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