Experiment 10: Kyle’s Aspirin
Abstract:
The purpose of this experiment was to find out what exactly is the active ingredient in Kyle’s
aspirin. In order to do this, the concentration of acetylsalicylic acid in Kyle’s
...
Experiment 10: Kyle’s Aspirin
Abstract:
The purpose of this experiment was to find out what exactly is the active ingredient in Kyle’s
aspirin. In order to do this, the concentration of acetylsalicylic acid in Kyle’s aspirin needs to be
determined. The identity of Kyle’s aspirin was C (may have been B, may have been a switch up in labels).
The hypothesis of the experiment was that Kyle needed to take a larger dosage of internet aspirin because
the concentration of his aspirin may not be enough. If Kyle's internet aspirin contains a lower
concentration of its active ingredient than the Bayer pills, then this explains why his dosage would be
doubled A series of titrations of Kyle’s aspirin, pure acetylsalicylic acid, and a Bayer were all completed
using NaOH as the titrant. For each of these titrations, the pH was tracked with a pH probe. For the Bayer
aspirin tablet (325 mg), the end point was at 14.40 mL, Kyle’s aspirin at 8.0 mL, and for the pure
compound. The pKa for the Bayer tablet is around 5.35. The pKa of the pure acetylsalicylic acid is around
5.27. The pKa of Kyle’s tablet is 5.77. Since these Kyle’s aspirin pKa is close to the Bayer tablet and pure
acetylsalicylic acid, it is safe to assume that acetylsalicylic acid was the active ingredient within Kyle’s
aspirin. The mass percent of acetylsalicylic acid in Kyle’s Aspirin was 47.0% and for the Bayer tablet it
was 87.7% (based off the label) and 84.2% (based off what was measured on scale). This just shows how
Kyle’s aspirin required him to take it twice the normal dosage because his aspirin is less concentrated
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