BioChemistry > QUESTIONS & ANSWERS > Queens University BCHM 218 PBA #2.pptx (All)
BCHM218 – FALL 2019 – PBA #2 This exercise will give you an opportunity to apply your understanding of some of the topics covered in Module 2. There are 6 questions in total. Please download a ... nd annotate/edit using Powerpoint, or Print the document and indicate your answers by hand. When finished, submit your answers as a PDF or JPG file to OnQ Name: Chloe Allan Student #: 20048028 This study source was downloaded by 100000784424693 from CourseHero.com on 05-30-2021 19:15:16 GMT -05:00 study resource was shared via Hero.comQuestion 1: (6 marks) The following diagram shows the parental DNA for two replication forks that are approaching one another from the left and right. (Note: Each linear line represents a single strand of DNA.) (a) Annotate the diagram (inside each fork) so that it accurately shows the result of nucleotide polymerization through the action of the replisome, prior to any activity by DNA Pol I and DNA ligase. Be sure to label the polarity of all DNA polymers! (Note: you don’t need to draw the replisome proteins. Just draw the DNA that is made.) (4 marks) (b) Add DnaB to the diagram to show where it would bind and its direction of movement if ATP were added to this protein-DNA complex. (2 marks) 5’ 5’ 3’ 3’ Fork 1 Fork 2 DnaB DnaB Red Arrow = RNA Primer Blue Arrow = Newly Synthesized DNA Strand 5’ 3’ 5’ 3’ Leading Strand Lagging Strand Leading Strand Lagging strand 5’ 5’ 3’ 3’ [Show More]
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