Respiratory transition in the newborn
➢ Respiratory function
• Established when cord is cut.
• Air inflates lungs with first breath.
• 4 factors influence the initiation of the 1st breath
➔ Chemical factors: hyper
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Respiratory transition in the newborn
➢ Respiratory function
• Established when cord is cut.
• Air inflates lungs with first breath.
• 4 factors influence the initiation of the 1st breath
➔ Chemical factors: hypercarbia, acidosis, and hypoxia which stimulate the resp center in the brain to initiate breathing.
➔ Sensory factors stimulate the first breath.
➔ Thermal factors are involved when the neonate exits the warm environment they have been used to.
➔ Mechanical factors such as removal of fluid from the lungs and replacements of air is the primary mechanical factor.
• The fetal chest compression that occurs during a vaginal birth increases the intrathoracic pressure and helps push fluid out of the lungs.
Circulatory transition in the newborn
• Successful adaptation in the neonate involves five major changes and increased aortic pressure
• Decreased venous pressure and increased systemic pressure
• Decreased pulmonary pressure
• Closure of the foramen ovale, the ductus arteriosus and the ductus venosus.
• Foramen ovale closes functionally 1-2 hrs anatomically 1-2 weeks
Hyperbilirubinemia in the newborn
• Unconjugated: fat soluble and toxic to body
• Normal bili = 4-6 mg/dl
• CONJUGATED: water soluble and nontoxic & conjugation happens in the liver
• Bili increases after birth r/t increased RBC
• Elevated bili = jaundice in the newborn - will rise over first 3-5 days and then decrease
• Total above 5 from unconjugated = yellowing of the skin, one of the most common reasons for newborn readmission
• Patho within 24 hours of life r/t polycythemia, blood incompatibilites, acidosis
• Physio after 24 hours of life r/t limitations and abnormalities of bili metabolism, r/t increased bili load because of polycythemia, shortened RBC lifespan, immature hepatic uptake and conjugation process
- delayed passage of meconium puts at risk Temperature regulation in the newborn Thermoregulation:
• Newborns have poor thermal stability due to excessive heat loss.
• It is closely related to rate of metabolism, oxygen consumption, amount of brown fat, and amount of subcutaneous tissue.
• Increased metabolic demands and/or increased oxygen demands can quickly lead to hypoglycemia (neonatal hypoglycemia is less than 40 mg/dl blood glucose level).
• Infants produce heat by increasing their metabolic rate, increasing muscular activity, or through
nonshivering thermogenesis (break down brown fat into heat).
• Four ways an infant loses heat:
▪ Convection: Air current blows heat away
▪ Radiation: Cold area, body radiates/loses heat
▪ Evaporation: When water evaporates it takes heat with it
▪ Conduction: If baby is put on cold surface it loses body heat to warm the surface
• Things you can do to help keep baby warm:
▪ Skin to skin contact, radiant warmer, wrap in warm blankets, use hats, monitor temperature, dry them after a bath, heat oxygen and humidify (if on oxygen therapy), teach family to keep them warm. You want their temp to stay around 98.6 but the normal range is 97.7-99.4.
Blood glucose changes in the newborn
• Normal BG
• 1-Day: 40-60 mg/dL
• >1-Day: 50-90 mg/dL
• Baby experiences an energy crunch @ the time of birth with the cutting of the umbilical cord and resultant removal of the maternal glucose supply (baby’s BG <15 mg/dL lower than maternal BG)
• This is significant because baby needs adequate amount of glucose in order to withstand the birth process and extrauterine life.
• Fuel sources are consumed at a faster rate because:
▪ The work of breathing
▪ Loss of heat when exposed to cold
▪ Activity
▪ Activation of muscle tone.
➢ Patho: As stores of liver and muscle glycogen and blood glucose decrease, the newborn compensates by changing form a predominantly carbohydrate metabolism to fat metabolism.
▪ Energy is derived from fat and protein as well as from carbohydrates.
• Assessment:
• 1st and 2nd hour after birth: blood glucose declines
• 3rd hour after birth: blood glucose reaches a steady level
Umbilical cord clamping and cutting
• Must use two clamps: one to cut off blood flow to placenta and one to keep baby form bleeding out
• Placement should be closer to baby than placenta and an inch or two between both clamps
• When cutting between two clamps: make sure clamps are tight enough and no blood is being exploited from umbilical cord
• After cutting: make sure two arteries and one vein are visible
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