WEEK ONE DIS ONE NR508 ADVANCED PHARMACOLOGY 2 week one dis one nr508 advanced pharmacology Emily, a relatively healthy 5’5”, 32-year-old young woman weighing 190 pounds, presents to your clini... c with hirsutism, anovulation, oligomenorrhea, and at times amenorrhea. Biochemical blood tests reveal elevated luteinizing hormone (LH, without a mid-cycle surge) and androgen elevation. She mentions that she also has a family history of irregular cycles, and that her grandmother experienced early menopause. She also states that she is sexually active, occasionally smokes (1 pack/month), and desires to be prescribed one medication to mitigate her symptoms, as well as, prevent her from becoming pregnant. Please provide a list of differential diagnoses, as well as an indication of your primary diagnosis. Once this has been completed, please indicate and describe your chosen pharmacological treatment with inclusion of dose and mechanism of action of your chosen prescription. Dr. Turpin and Classmates, Primary Differential Diagnosis #1: Polycystic Ovarian Syndrome. Polycystic Ovarian Syndrome (PCOS) is characterized by an imbalance of sex hormones (androgens) combined with irregular periods, hirsutism, and obesity with possible infertility and potential ovarian cysts. With the advent of epidemic obesity and its relationship with metabolic syndrome as well as insulin resistance more research has been focused on PCOS as it relates to the pathology of this disease process. In the past PCOS was dealt with by specialists but it is now seen most often in the primary care offices for more aggressive treatment. [Show More]
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