BISC 3221 EXAM 1 REVIEW
Chapter 2 The Cell
Mitotic rate = longer life expectancy, the slower the mitotic rate
Skeletal muscle cells have most mitochondria bc need E for movement
Glucose and aa = facilitated dif
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BISC 3221 EXAM 1 REVIEW
Chapter 2 The Cell
Mitotic rate = longer life expectancy, the slower the mitotic rate
Skeletal muscle cells have most mitochondria bc need E for movement
Glucose and aa = facilitated diffusion
Cytokinesis begins in LATE ANAPHASE
DNA not dividing is in form chromatin
Strength and rigidty, and anchoring positions of major organelles = microtubules
Endocytosis is an active process, requires E
Connexons associated with gap junctions
o BE ABLE TO ID diff types of junctions, what anchors to basement membrane etc
Flagella = microtubules
Chapter 5: The Skeletal system – osseous tissue and bone structure; WATCH VIDEO FOR
EXAM
Condition aka adult rickets, characterized by a gradual softening and being of bone dues
to poor mineralization = osteomalacia
*Bone process is an expanded articular end of the epiphysis, often separated from the
diaphysis by a narrower neck = head
Which of following most likely to be a term associated with an articulation point? =
trochanter, tubercle, condyle, process
Choose INCORRECT statement regarding age-related skeletal abnormality =
administration of calcitionin by nasal spray appears to prevent the development of
osteoporosis wrong!!
o Vertebrae may collapse due to osteoporosis, distorting the .. is true!
Potassium isn’t a mineral necessary for normal bone growth (need it for muscles)
Bone maintenance and repair = vitamin A, C, and D; most prone to vitamin D
deficiencies = people from northern climates
Yellow bone marrow found in the medullary cavity (KNOW DIAGRAM OF BONE w/
MARROW)
Hormones stimulate osteoclasts and osteoblasts = PTH
o Know diff between osteoclasts and osteoblasts!
Congenital skeletal disorders results from excessive cartilage formation at epiphyseal
cartilages = Marfan syndrome
The deposition of calcium salts in tissue other than bone is called calcification.
Not function of periosteum= Site for hematopoiesis
**Which of the following processes is formed where tendons and ligaments attach =
trochanter (also know definitions of condyle, trochlea, and sulcus)
o know difference between tendons and ligaments = ESSAY QUESTION TO
DIFFERENTIATE WHERE THEY ATTACH
Spongy bone resides in the epiphyses and is better equipped to resist forces from many
directions.
o Ball and socket joints .. not good to kick at shin from front bc shatters or breaks Vitamin A stimulates osteoblast activity
Bone opening represents a rounded passageway fro blood vessels and nerves = foramen
Osteocytes are mature bone cells
Replacing embryonic tissues with bone = ossification
Pituitary dwarfism results from inadequate production of GH before puberty
If both parents have achondroplasia, which of the following statements is TRUE?
o Changes are that 50 percent of the children will be affected to some degree.
Which of the following is the clinical term for an infection of bone and bone marrow =
osteomyelitis
GH and thyroxine are hormones that stimulate bone growth
Fracture occurs when an affected area is shattered into a multitude of bony fragments =
comminuted fracture – caused by excessive force and trauma not like a slide tackle in
soccer;KNOW THE COMMON ONES
Small. Flat, oddly shaped bones found between the flat bones of the skull = sutural bones
Essay type question of endochondral ossification; 3, 5, 2, 6, 4, 1
Chapter 3 Tissues and Early Embryology
Where they would be found, type of structures, where to find cilia (COLUMNAR, have
goblet cells interspaced) vs microvilli
Which tissue formed by differentiation of embryonic connective tissue = loose
connective tissue and dense connective tissue
Stratified squamous epithelium keratinized = palmar skin (palmar = on palm)
Dense connective tissue attaches skeletal muscle to bones or cartilage = tendons (KNOW
TENDONS AND LIGAMENTS)
Membrane that surrounds abdomen and covers surfaces of enclosed organs = peritoneum
Regarding fluid connective tissue, which bathes the body’s cells = interstitial fluid
Type of membrane lines body cavities that lack openings, thus minimizing friction
between opposing surfaces = serous; not synovial bc more of a joint
Pleuritis, pericarditis, and peritonitis are inflammatory conditions affecting SEROUS
MEMBRANES
Connective tissues do not produce specialized secretions
Functions to distribute oxygen and nutrients, cushions socks, and lubricate cartilages
within the joint = synovial membrane
Cardiac muscle = branched, striated, and uninucleate
Lumen = a hollow duct that is formed by the lining of cuboidal cells
**Loose connective tissue separates skin form deeper structures allowing elasticity that
provides independent movement = areolar tissue
laying down matrix of bone = osteoblasts
know cellularity, polarity, avascular for epithelial
membrane forms barrier that resist pathogens by secreting = mucous membrane -- >
know where found
tissue that makes up tendons and ligaments = dense tissue
Chapter 8: Articulations
*Articulation between the femur and the tibia = diarthorsis NOT Characteristic of synovial joints = in a joint cavity filled with synovial fluid, allows
slight movement no bc synovial allows large range of motion
Movement of foot allows for standing on tiptoe = plantar flexion (KNOW ALL THOSE
TERMS)
Type of movement NOT possible at the radiocarpal joint = rotation
The vertebral column can do all of the following movements except: rotation, flexion,
extension, medial flexion
know diff between spondylolysis and spondylolisthesis
KNOW SPINAL COLUMN for other examshow many vertebrae you have, diff
segments, and knowing their numbers
know did between spondylolysis and spondylolisthesis
Bursae:: small, fluid-filled pockets that
Synovial joints move(s) in rotation == ball-and-socket joint and pivot joint
Which bone is medial after pronation? = radius
The sternoclavicular joint is capable of which of the following movements? slight
circumduction and gliding
MANDIBLE, SHOULDER, KNEE know in detail!!
Why is the TMJ unique compared to other synovial joints
o The articulating surfaces on the temporal bone and mandible are covered with
fibrous cartilage
Which of the following is an angular motion where the joint moves away from the
longitudinal axis on a frontal bone = abduction
What determines the amount of movement at any segment of the vertebral column =
intervertebral discs
Articulation between bones and skull = suture
Which classification of articulation is represented by the distal articulation between the
tibia and fibula = amphiathrosis
What time of articulation is present between facets of vertebra C2-S1 = symphysis
SHORT ANSWER
1. Whats the significance of the orientation of the trabecular in spongy bone? Provide
a specific example, discussing how trabecular structure leads to its function(s).
The trabeculae of spongy bone form an open network, creating strength to deal
with stress from the side. Trabeculae are oriented along the stress lines, which
makes spongy bone capable of resisting stresses applied from many different
directions. For example, at the proximal epiphysis, the trabeculae transfer forces
from the hip across the metaphysis to the femoral shaft.
2. What is the clinical importance of tension lines/cleavage lines of the skin?
Tension lines reflect the parallel orientation of collagen and elastic fibers in the
dermis. In certain areas of the body, there is a pattern of these tension/cleavage
lines due to stress or a specific type of movement; they are aligned to resist
applied forces. To reduce scar formation (extensive damage to the fibers),
surgeons try to cut parallel to tension lines.
3. What are the main structural differences between cartilage and bone? Most bones during formation start out as cartilage tissue. Cartilage is soft elastic
and flexible while bone is hard, inelastic, and tough. The gel matrix of cartilage is
composed chondroitin sulfate, whereas the solid matrix of bone is composed of
calcium phosphate crystals (hydroxyapaptite). Cartilage cells are chondrocytes,
whereas bone cells are osteocytes. Cartilage is avascular, bone is vascular; tis
makes sense because bones require oxygen and nutrients unlike cartilage.
Cartilage surface consisits of fibrous perichondrium, while bone surfaces
consists of periosteum.
SHORT ESSAY
1. How does melanin protect the skin from the effects of UV light?
Melanin are produced and stored within melanocytes; its production creates
natural skin color and tan. In response to exposure to UV light, melanocytes
increase the rate of melanin formation. Protective because melanin absorbs UV
radiation. A little UV radiation is necessary bc skin requires it to form vitamin D,
but too much UV radiation may damage chromosomes and cause widespread
tissue damage similar to that caused by mild to moderate burns.
2. What kind of tissue(s) would most likely be found in a tissue sample taken from the
interior of the epiphysis of the femur?
Spongy bone makes up the internal framework of the epiphyses of the femur. Also extensive areas
of red bone marrow (important sites of blood cell formation) filling in the spaces of the spongy
bone.
3. Why is skeletal muscle called striated voluntary muscle?
Striated bc have a striped appearance under the microscope; distinct series of
alternating light/dark bands perpendicular to long axis
Voluntary control
Striated refers to a banded appearance, and voluntary means the fiber won't contract
unless stimulated by neurons.
4. Predict the consequences of non-functional cilia in the respiratory airways.
Found lining the respiratory tract
Ciliated epithelium moves substances over the apical surface and beat in
coordinated fashion to move mucus from lungs toward throat
Mucus traps particles and pathogens and carries them away from lungs
Mucus would still be present, but would linger in the respiratory tract, person will
cough
Mucous accumulate
5. What is the basic anatomical pattern that humans and other vertebrate share?6. What are the components of a synovial joint?
Six basic characteristics:
o A joint capsule = has outer layer of thick, dense, regularly arranged
connective tissue and inner synovial membrane
o Presence of articular cartilages = cover bony surfaces (shock absorber and
reduce friction)
o Filled with synovial fluid
o A synovial membrane
o Accessory structures (cartilage, ligaments, tendons, bursae)
o Sensory nerves and blood vessels (blood vessels supply the exterior and
interior of the joint)
7. Why do human beings lose height as they reach old age?
Might:
Difference between tendons and ligaments
Tendons and ligaments are both types of dense regular connective tissue
Tendons: connect muscle to bone; collagen fibers run along longitudinal axis of the
tendon and transfer the pull of contracting muscle to the bone or cartilage
Ligaments: connect bone to bone
o Elastic ligaments: contain elastic fibers allowing for a modest amount of
stretching
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